57915-78-3

Usage

Chemical Properties

White low melting solid

InChI:InChI=1/C7H5BrCl2/c8-4-5-2-1-3-6(9)7(5)10/h1-3H,4H2

Upstream product

• 38594-42-2 2,3-dichlorobenzyl alcohol 
• 7789-60-8 phosphorus tribromide 
• 50-45-3 2,3-dichlorbenzoic acid 
• 2905-54-6 2,3-Dichlorobenzoic acid methyl ester 

Downstream Products

• 39959-98-3 ethyl 2-cyano-3-(2,3-dichlorophenyl)propanoate 
• 35659-60-0 1-(2,3-Dichlorbenzyl)-1-methylhydrazin 
• 244220-19-7 C₈H₅Cl₂NS 
• 1028450-12-5 ethyl 6-[(2,3-dichlorobenzyl)sulfanyl]cyclohex-1-ene-1-carboxylate 
• 1092584-89-8 3-benzyl-6-(2,3-dichlorobenzyl)-1,3,4-trimethylpiperazine-2,5-dione 
• 1374306-31-6 C₁₃H₉Cl₃N₄O 
• 1374306-32-7 C₁₃H₉Cl₃N₄OS 
• 1374306-10-1 3-(2,3-dichlorobenzyl)-2-(methylthio)-5-morpholino-[1,2,4]triazolo[1,5-a]pyrimidin-7(3H)-one 
• 1374306-33-8 C₁₅H₁₁Cl₃N₄O 
• 1374306-11-2 2-cyclopropyl-3-[(2,3-dichlorophenyl)methyl]-5-(4-morpholinyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(3H)-one 
• 1374306-15-6 3-[(2,3-dichlorophenyl)methyl]-2-(methylthio)-5-(4-pyridinyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(3H)-one 
• 1374306-09-8 3-[(2,3-dichlorophenyl)methyl]-2-methyl-5-(4-morpholinyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(3H)-one 
• 1374306-12-3 3-[(2,3-dichlorophenyl)methyl]-2-methyl-5-(2-methyl-4-morpholinyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(3H)-one 
• 1415664-00-4 C₂₂H₁₆Cl₂N₆S 

Relevant academic research and scientific papers

Pyrazolopyrimidine derivatives as PI3 kinase inhibitors

PI3Kβ selective compounds having the structure

PYRAZOLOPYRIMIDINE DERIVATIVES AS PI3 KINASE INHIBITORS

The present invention relates to compounds of formula (I) in which R1, R2, R3 and n have the meaning given in the specification and also relates to the use of these pyrazolopyrimidine derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide 3'OΗ kinase family (hereinafter PI3 kinases), wherein the compounds of formula (I) are described as selective inhibitors of PI3K[beta] activity.