579470-27-2Relevant academic research and scientific papers
Ru-catalyzed hydroamidation of alkenes and cooperative aminocarboxylation procedure with chelating formamide
Ko, Sangwon,Han, Hoon,Chang, Sukbok
, p. 2687 - 2690 (2003)
(Matrix presented) A strategy of chelation-assisted activation of formamide was employed to achieve hydroamidation of alkenes to generate one-carbon-elongated amides in moderate to good selectivity and yields. Also reported is the two-metal-catalyzed cooperative aminocarboxylation of aryl iodides, in which Ru is presumed to catalyze decarbonylation of formamide to release carbon monoxide and amine for the subsequent Pd-catalyzed aminocarboxylation routes, thus enabling the net transformation to be performed in the absence of external CO pressure.
