579475-29-9

Basic information

• Product Name: 3-Bromo-6-(cyclopropyl)pyridine
• Synonyms: 3-Bromo-6-(cyclopropyl)pyridine
• CAS NO: 579475-29-9
• Molecular Formula: C₈H₈BrN
• Molecular Weight: 198.062
• Mol File: 579475-29-9.mol

Chemical Properties

• Boiling Point: 242.9±28.0 °C(Predicted)
• Appearance: /
• Density: 1.561±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.55±0.22(Predicted)
• CAS DataBase Reference: 3-Bromo-6-(cyclopropyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-6-(cyclopropyl)pyridine(579475-29-9)
• EPA Substance Registry System: 3-Bromo-6-(cyclopropyl)pyridine(579475-29-9)

Safety Data

• Hazardous Substances Data: 579475-29-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Bromo-6-(cyclopropyl)pyridine is used as a building block for the preparation of various pharmaceuticals. Its unique structure and functional groups make it a promising candidate for the development of new drugs with potential biological activities.
Used in Agrochemical Industry:
3-Bromo-6-(cyclopropyl)pyridine is also utilized in the production of agrochemicals. As an intermediate, it plays a crucial role in the synthesis of compounds with pesticidal or herbicidal properties, contributing to the advancement of agricultural chemistry.
Used in Organic Synthesis:
3-Bromo-6-(cyclopropyl)pyridine is employed as a valuable intermediate in organic synthesis. Its versatile structure allows for further functionalization and modification, enabling the creation of a wide range of chemical compounds with diverse applications in various industries.

Upstream product

• 624-28-2 2,5-dibromopyridine 
• 23719-80-4 cyclopropylmagnesium bromide 
• 4333-56-6 cyclopropyl bromide 
• 203861-73-8 cyclopropylzinc chloride 

Downstream Products

• 893567-09-4 2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 
• 579475-27-7 3-(6-cyclopropyl-pyridin-3-yl)-benzonitrile 

Relevant articles and documents

HETEROCYCLIC COMPOUND AS CSF-1R INHIBITOR AND USE THEREOF

The present invention relates to a class of isoindolinone derivatives and use thereof in the preparation of a medicament for treating diseases associated with a novel colony stimulating factor 1 receptor (CSF-1R) inhibitor. In particular, the present invention relates to a compound of formula (I) and a pharmaceutically acceptable salt thereof or a stereoisomer thereof.

NOVEL SUBSTITUTED BIARYL COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS

Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.

NOVEL COMPOUNDS

The invention provides compounds of formula (I): wherein R1, R2, A, A1 and B are as defined in the specification; processes for their preparation; pharmaceutical compositions containing them; a process for preparing the ph

Acetylenyl-pyrazolo-pyrimidine derivatives

The present invention relates to compounds of formula (I): wherein R1 to R3, A, M, L, E, G, and J are as defined in the description and claims. The invention also relates to a process for the manufacture of such compounds, pharmaceutical compositions containing them, and methods for treating CNS disorders.

COMBINATION OF MGLUR2 ANTAGONIST AND ACHE INHIBITOR FOR TREATMENT OF ACUTE AND/OR CHRONIC NEUROLOGICAL DISORDERS

The present invention relates to a method of treatment or prevention of acute and/or chronic neurological disorders, to a pharmaceutical composition comprising an inhibitor of acetylcholinesterase (AChE inhibitor) and a metabotropic Glutamate receptor 2 antagonist (mGluR2 antagonist), to the use of an AChE inhibitor and a mGluR2 antagonist in the preparation of a medicament, and. to kits comprising an AChE inhibitor and a mGluR2 antagonist.

2-pyridinyl-3(4-methylsulfonyl)phenylpyridines: Selective and orally active cyclooxygenase-2 inhibitors

A series of novel 2-pyridinyl-3-(4-methylsulfonyl)phenylpyridines has been synthesized and evaluated with respect to their ability to inhibit the isozymes of cyclooxygenase, COX-1, and COX-2. Optimum COX-2 activity is observed by introduction of a substituent at C5 of the central pyridine. 5- Chloro-3-(4-methylsulfonyl)phenyl-2(2-methyl-5-pyridinyl)pyridine 33 was identified as the optimum compound in this series.