893567-09-4

Basic information

• Product Name: 6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER
• Synonyms: 6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER;6-Cyclopropylpyridine-3-boronic acid pinacol ester;6-Cyclopropylpyridine-3-boronic acid pinacol ester 6-(Cyclopropyl)pyridine-3-boronic acid pinacol ester;2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl);6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PICOL ESTER
• CAS NO: 893567-09-4
• Molecular Formula: C₁₄H₂₀BNO₂
• Molecular Weight: 245.1251
• Mol File: 893567-09-4.mol

Chemical Properties

• Boiling Point: 354.102 °C at 760 mmHg
• Flash Point: 167.955 °C
• Appearance: /
• Density: 1.073 g/cm³
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: 5.90±0.24(Predicted)
• CAS DataBase Reference: 6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER(893567-09-4)
• EPA Substance Registry System: 6-CYCLOPROPYL-3-PYRIDINYL BORONIC ACID PINACOL ESTER(893567-09-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37-60
• TSCA: No
• Hazardous Substances Data: 893567-09-4(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
6-Cyclopropyl-3-pyridinyl boronic acid pinacol ester is used as a reagent in organic synthesis for the formation of carbon-carbon and carbon-heteroatom bonds, facilitating the creation of complex molecular structures.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 6-Cyclopropyl-3-pyridinyl boronic acid pinacol ester is used as a building block for the development of pharmaceuticals, contributing to the discovery of new drugs and therapeutic agents.
Used in Agrochemical Research:
6-Cyclopropyl-3-pyridinyl boronic acid pinacol ester is utilized in agrochemical research, where it aids in the synthesis of new compounds with potential applications in crop protection and pest control.
Used in Materials Science Research:
In materials science, 6-Cyclopropyl-3-pyridinyl boronic acid pinacol ester is employed in the development of new materials with unique properties, such as advanced polymers and composites.
Used in the Suzuki-Miyaura Coupling Reaction:
6-Cyclopropyl-3-pyridinyl boronic acid pinacol ester is used as a key component in the Suzuki-Miyaura coupling reaction, a widely used method in cross-coupling reactions for the formation of carbon-carbon bonds, particularly in the synthesis of biologically active compounds and complex organic molecules.

Upstream product

• 73183-34-3 bis(pinacol)diborane 
• 579475-29-9 3-bromo-6-(cyclopropyl)pyridine 

Downstream Products

• 1206612-54-5 methyl 4-(4-(5-(6-cyclopropylpyridin-3-yl)thiazol-2-yl)-tetrahydro-2H-pyran-4-yl)benzoate 
• 1262044-06-3 N-(3-(1,3,4-oxadiazol-2-yl)phenyl)-6-cyclopropyl-3,4'-bipyridine-2'-carboxamide 

Relevant articles and documents

THERAPEUTIC COMPOUNDS

The present embodiments relate to substituted heterocyclic derivative therapeutic compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition

SUBSTITUTED HETEROCYCLIC SULFONAMIDE COMPOUNDS USEFUL AS TRPA1 MODULATORS

The invention is concerned with the compounds of formula I or II: and salts thereof. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I or II as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.

NOVEL COMPOUNDS

The invention provides compounds of formula (I): wherein R1, R2, A, A1 and B are as defined in the specification; processes for their preparation; pharmaceutical compositions containing them; a process for preparing the ph