57978-47-9 Usage
General Description
2-(3-Methoxy-phenylamino)-nicotinic acid is a chemical compound with the molecular formula C13H12N2O4. It is a derivative of nicotinic acid and features a 3-methoxyphenylamino group attached to the 2-position of the nicotinic acid ring. 2-(3-Methoxy-phenylamino)-nicotinic acid is often used as a research tool in the study of nicotinic acid receptors and their potential pharmacological applications. It may also have potential therapeutic uses due to its ability to modulate nicotinic acid receptor activity. Additionally, it has been investigated for its potential anti-inflammatory and neuroprotective properties, making it a compound of interest in the fields of neuropharmacology and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 57978-47-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,9,7 and 8 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 57978-47:
(7*5)+(6*7)+(5*9)+(4*7)+(3*8)+(2*4)+(1*7)=189
189 % 10 = 9
So 57978-47-9 is a valid CAS Registry Number.
57978-47-9Relevant articles and documents
Antiallergy Agents. 1. Substituted 1,8-Naphthyridin-2(1H)-ones as Inhibitors of SRS-A Release
Sherlock, Margaret H.,Kaminski, James J.,Tom, Wing C.,Lee, Joe F.,Wong, Shing-Chun,et al.
, p. 2108 - 2121 (2007/10/02)
A novel class of antiallergy agents, the substituted 1,8-naphthyridin-2(1H)-ones, is described.The present compounds are orally active, potent inhibitors of allergic and nonallergic bronchospasm in animal models.Structure-activity studies of the lead compound in this sereis, 1-phenyl-3-n-butyl-4-hydroxynaphthyridin-2(1H)-one (11), identified three compounds of interest, 1-phenyl-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one (12), 1-(3'-chlorophenyl)-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one (87), and 1-(3'-methoxyphenyl)-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one (89).The mechanism of antiallergy activity may involve inhibition of the release of the sulfidopeptide leukotrienes. 1-Phenyl-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one, Sch 33303 (12), was selected for preclinical development as an antiallergy agent.
