5798-78-7

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 873-75-6 4-bromobenzenemethanol 
• 75-44-5 phosgene 

Downstream Products

• 40297-81-2 Z(4-Br)-DL-Phe 
• 96447-82-4 4-Brombenzyloxycarbonyl-DL-valin 
• 133230-88-3 (p-bromobenzyloxycarbonyl)-L-phenylalanyl-L-histidine 
• 133230-77-0 (p-bromobenzyloxycarbonyl)-L-phenylalanyl-L-histidine methyl ester 
• 1037515-62-0 C₁₉H₂₃BrN₄O₆ 
• 35280-90-1 5-benzyl-10b-hydroxy-2-methyl-3,6-dioxo-octahydro-imidazo[1,2-a]pyrrolo[2,1-c]pyrazine-1-carboxylic acid 4-bromo-benzyl ester 
• 35821-51-3 N-p-bromobenzyloxycarbonyl-L-alanyl-L-phenylalanyl-L-proline p-nitrophenyl ester 
• 1026426-08-3 (S)-2-(4-Bromo-benzyloxycarbonylamino)-3-{2-[3-(4-carbamimidoyl-phenyl)-4,5-dihydro-isoxazol-5-yl]-acetylamino}-propionic acid methyl ester 
• 95295-83-3 4-Brombenzyloxycarbonyl-DL-methionin 
• 97237-55-3 4-Brombenzyloxycarbonyl-DL-leucin 
• 81002-77-9 2-Oxo-3-p-brombenzyloxycarbonyl-α-D-ribofurano<1',2':4,5>-oxazolidin 
• 80070-85-5 bis(p-bromobenzyl) peroxydicarbonate 
• 40297-81-2 (p-bromobenzyloxycarbonyl)-L-Phe-OH 

Relevant academic research and scientific papers

COLCHICINE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PREPARING SAID DERIVATIVES, AND PHARMACEUTICAL COMPOSITION COMPRISING SAID DERIVATIVES

The present invention relates to colchicine derivatives expressed in chemical formula 1, or to pharmaceutically acceptable salts thereof, to a method for preparing said derivatives, and to a pharmaceutical composition comprising said derivatives. The colchicine derivatives according to the present invention exhibit superior immunomodulatory effects as compared with conventional immunomodulators or colchicines, and therefore can be valuably used as an immunomodulator for modulating an acute or chronic immune response in organ transplantation.

Studies on the structure-activity relationship of 1,3,3,4-tetra-substituted pyrrolidine embodied CCR5 receptor antagonists. Part 1: Tuning the N-substituents

A novel series of CCR5 antagonists has been identified, utilizing the lead, nifeviroc, which were further modified based on bioisosteric principles. Lead optimization was pursued by balancing potential toxicity and potency. Potent analogues with low toxic properties were successfully developed by formation of urea and amide bonds at the nitrogen at position 4- of the pyrrolidine ring.

KINETIC LAWS OF THE THERMAL DECOMPOSITION OF SUBSTITUTED DIBENZYL PEROXYDICARBONATES IN ORGANIC MEDIA

1.The relative extents of unimolecular and induced decomposition in thethermolysis of substituted dibenzyl peroxydicarbonates were investigated.They are influenced substatially by the reaction medium and also by the structure of the peroxydicarbonate take