5798-94-7

Usage

Purification Methods

Crystallise the hydroxamic acid from H2O (m 249o) or from EtOH (m 232o dec). It sublimes at m 235o. It complexes with metals. [Beilstein 10 IV 221.]

InChI:InChI=1/C7H6BrNO3/c8-4-1-2-6(10)5(3-4)7(11)9-12/h1-3,10,12H,(H,9,11)

Upstream product

• 89-73-6 salicylhydroxamic acid 
• 4068-76-2 5-bromo-2-hydroxy-benzoic acid methyl ester 

Downstream Products

• 14733-73-4 5-bromo-1,3-benzoxazol-2(3H)-one 
• 65685-50-9 3-Hydroxy-5-brom-1,2-benzisoxazol 
• 63482-65-5 7-bromo-3,3a-dihydro-2H-benzo[e]isoxazolo[3,2-b][1,3]oxazin-9-one 
• 63482-57-5 6-bromo-2-(2-chloro-ethyl)-3-hydroxy-2,3-dihydro-benzo[e][1,3]oxazin-4-one 

Relevant academic research and scientific papers

FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS

The present disclosure relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given

Synthesis and biological evaluation of D-amino acid oxidase inhibitors

D-Amino acid oxidase (DAAO) catalyzes the oxidation of D-amino acids including D-serine, a full agonist at the glycine site of the NMDA receptor. A series of benzo[d]isoxazol-3-ol derivatives were synthesized and evaluated as DAAO inhibitors. Among them,

Mixed anhydrides of carbamic and hydroxamic acids

A base precursor represented by the following general formula (A) or (B): STR1 wherein A1, A2, A5, A6, A7, and A8 each represents a hydrogen atom, an alkyl group, a substituted alkyl group, a cycloalkyl group, an alkenyl group, an aralkyl group, an aryl group, a substituted aryl group, an acyl group, or a heterocyclic group, and A1 and A2 can combine to form a ring and two of A5, A6, A7, and A8 can combine to form a ring, A3 and A4 each represents a hydrogen atom, an alkyl group, a substituted alkyl group, a cycloalkyl group, or an aralkyl group, and A3 and A4 can combine to form a ring or A3 and A4 can be a double bond forming an imino group from STR2 and X represents a nucleophilic group.