63482-65-5

Basic information

• Product Name: 7-bromo-3,3a-dihydro-2H,9H-[1,2]oxazolo[3,2-b][1,3]benzoxazin-9-one
• Synonyms: 7-Bromo-3,3a-dihydro-2H,9H-isoxazolo(3,2-b)(1,3)benzoxazin-9-one; 7-Bromo-3,3a-dihydro-2H,9H-isoxazolo[3,2-b][1,3]benzoxazin-9-one
• CAS NO: 63482-65-5
• Molecular Formula: C₁₀H₈BrNO₃
• Molecular Weight: 270.0794
• Mol File: 63482-65-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 456.5°C at 760 mmHg
• Flash Point: 229.9°C
• Density: 1.82g/cm³
• Vapor Pressure: 1.61E-08mmHg at 25°C
• Refractive Index: 1.688
• CAS DataBase Reference: 7-bromo-3,3a-dihydro-2H,9H-[1,2]oxazolo[3,2-b][1,3]benzoxazin-9-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-bromo-3,3a-dihydro-2H,9H-[1,2]oxazolo[3,2-b][1,3]benzoxazin-9-one(63482-65-5)
• EPA Substance Registry System: 7-bromo-3,3a-dihydro-2H,9H-[1,2]oxazolo[3,2-b][1,3]benzoxazin-9-one(63482-65-5)

Safety Data

• Hazardous Substances Data: 63482-65-5(Hazardous Substances Data)

Upstream product

• 5798-94-7 5-bromo-N,2-dihydroxybenzamide 
• 63482-57-5 6-bromo-2-(2-chloro-ethyl)-3-hydroxy-2,3-dihydro-benzo[e][1,3]oxazin-4-one 

Relevant articles and documents

Synthesis and anti inflammatory activity of 3,3a dihydro 2H,9H isoxazolo[3,2 b] [1,3]benzoxazin 9 ones and related compounds

A series of 3,3a-dihydro-2H,9H-isoxazolo[3,2-b]-[1,3]benzoxazin 9-ones was synthesized and evaluated for anti-inflammatory, antipyretic and analgesic activity. Since many of these compounds exhibited promising activity, particularly in the anti-inflammatory tests, a number of homologous 2,3,4,4a-tetrahydro-10H-1,2-oxazino[3,2-b]-[1,3]benzoxazin 10-ones and one 3,4,5,5a-tetrahydro-2H, 11H-1,2-oxazepino [3,2-b] [1,3]benzoxazin-11-one, the 9-chloro analog, were also prepared and evaluated. The expanded ring members were generally less active than the tricyclic compounds containing the isoxazolidine rng.