57981-22-3Relevant articles and documents
Formal Bromine Atom Transfer Radical Addition of Nonactivated Bromoalkanes Using Photoredox Gold Catalysis
Zidan, Montserrat,McCallum, Terry,Swann, Rowan,Barriault, Louis
supporting information, p. 8401 - 8406 (2020/11/03)
Organic transformations mediated by photoredox catalysis have been at the forefront of reaction discovery. Recently, it has been demonstrated that binuclear Au(I) bisphosphine complexes, such as [Au2(μ-dppm)2]X2, are capable of mediating electron transfer to nonactivated bromoalkanes for the generation of a variety of alkyl radicals. The transfer reactions of bromine, derived from nonactivated bromoalkanes, are largely unknown. Therefore, we propose that unique metal-based mechanistic pathways are at play, as this binuclear gold catalyst has been known to produce Au(III) Lewis acid intermediates. The scope and proposed mechanistic overview for the formal bromine atom transfer reaction of nonactivated bromoalkanes mediated by photoredox Au(I) catalysis is presented. The methodology presented afforded good yields and a broad scope which include examples using bromoalkanes and iodoarenes.
Reductive alkylation of β-alkoxy aziridines: New route to substituted allylic amines
Rosser, Clare M.,Coole, Susannah C.,Kirby, Jonathan P.,O'Brien, Peter,Caine, Darren
, p. 4817 - 4819 (2007/10/03)
(Chemical Equation Presented) A new route to substituted cyclic allylic amines via the reductive alkylation of β-alkoxy aziridines using excess alkyllithium reagents is described.
