57998-72-8

Usage

Uses

Used in Organic Synthesis:
2,5-dibromo-3,6-dimethoxycyclohexa-2,5-diene-1,4-dione is used as an intermediate in the synthesis of various organic compounds. Its unique structure and reactivity make it a valuable building block for creating complex molecules.
Used in Pharmaceutical Production:
2,5-dibromo-3,6-dimethoxycyclohexa-2,5-diene-1,4-dione is utilized in the production of pharmaceuticals, where its strong oxidizing properties can be harnessed to create new drug molecules with potential therapeutic applications.
Used in Cancer Treatment Research:
2,5-dibromo-3,6-dimethoxycyclohexa-2,5-diene-1,4-dione is used as a cytotoxic agent in cancer research. Its potent cytotoxic effects have made it a subject of interest for scientists exploring new cancer treatments, with the aim of developing more effective therapies for patients.
Used in Chemical Reactions:
Due to its strong oxidizing properties, 2,5-dibromo-3,6-dimethoxycyclohexa-2,5-diene-1,4-dione is used as a reagent in various chemical reactions. Its ability to act as an oxidant can facilitate the synthesis of other compounds and contribute to the advancement of chemical research.
Safety Considerations:
Given the reactivity and potential health hazards associated with 2,5-dibromo-3,6-dimethoxycyclohexa-2,5-diene-1,4-dione, it is crucial to handle and store 2,5-dibromo-3,6-dimethoxycyclohexa-2,5-diene-1,4-dione with extreme care. Proper safety measures, including the use of protective equipment and adherence to safety protocols, are essential to minimize risks to health and the environment.

Upstream product

• 3117-03-1 2,5-dimethoxyquinone 
• 106-51-4 p-benzoquinone 

Downstream Products

• 22826-69-3 2.5-Dimethoxy-3.6-diazido-1.4-benzochinon 
• 339094-44-9 2,5-dibromo-3-[2-(1,1-dimethyl-allyl)-1H-indol-3-yl]-6-methoxy-[1,4]benzoquinone 
• 882853-61-4 C₃₀H₁₅BrF₁₇NO₆S 
• 78708-35-7 asterriquinone B1 
• 78860-34-1 2-[2-(1,1-dimethyl-2-propenyl)-1H-indol-3-yl]-3,6-dihydroxy-5-[7-(3-methyl-2-butenyl)-1H-indol-3-yl]-2,5-cyclohexadiene-1,4-dione 
• 28293-19-8 2,5-diamino-3,6-dimethoxy-[1,4]benzoquinone 
• 1110631-78-1 2-bromo-3,6-dimethoxy-5-(3-thiophene)-1,4-benzoquinone 
• 51860-94-7 2,5-dimethoxy-3,6-bis(4-methoxyphenyl)-1,4-benzoquinone 
• 1110631-68-9 4’-(benzyloxy)-4-bromo-3,6-dimethoxy-[1,1’-biphenyl]-2,5-dione 
• 55458-24-7 3,6-diphenyl-2,5-dimethoxy-1,4-benzoquinone 
• 548-59-4 2,5-dihydroxy-3,6-diphenyl-1,4-benzoquinone 

Relevant academic research and scientific papers

Synthesis of a focused chemical library based on derivatives of embelin, a natural product with proapoptotic and anticancer properties

The synthesis of new derivatives of embelin, a natural inhibitor of X-linked inhibitor of apoptosis protein (XIAP) is described. The design of these new molecules involved introduction of aromatic groups directly linked to the benzoquinone core. To allow a large flexibility in the nature and the length of the added chain, the strategy involves first aSuzuki-Miyaura reaction with functionalized aromatics, yielding a first generation of molecules. Then, by appropriate use of the functional groups, a second generation of representative embelin derivatives was prepared.

An approach to 3,6-disubstituted 2,5-dioxybenzoquinones via two sequential Suzuki couplings. Three-step synthesis of leucomelone

(Chemical Equation Presented) Two sequential Suzuki coupling reactions have been developed for efficient synthesis of synthetically and biologically important 3,6-disubstituted 2,5-dioxybenzoquinone architectures in a highly chemoselective controlled mann

Fluorous-tagged indolylboron for the diversity-oriented synthesis of biologically-attractive bisindole derivatives

The diversity-oriented synthesis of bisindole derivatives to construct concise libraries using consecutive cross-coupling reactions and prepare new sulfonamide type fluorous protecting groups is presented. The Royal Society of Chemistry 2006.

Microwave induced selective bromination of 1,4-quinones and coumarins

Microwave irradiation accelerates the bromination of 1,4-quinones and coumarins with (i) bromide adsorbed on neutral alumina in 'dry media' and (ii) with iodine monobromide on acetic acid as compared to the reactions run at room temperature. Bromination takes place selectively at active quinonoid position in 1,4-quinones and at α,β-double bond in coumarins.