57999-73-2

Upstream product

• 134529-30-9 (E)-3-benzylidene-5-(4-methoxyphenyl)furan-2(3H)-one 
• 57999-79-8 α-phenacyl-p-methoxycinnamic acid 

Downstream Products

• 57999-76-5 4-(4-methoxybenzyl)-6-phenylpyridazin-3(2H)-one 
• 77811-71-3 2-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-4-oxo-4-phenyl-butyric acid [1-(4-nitro-phenyl)-meth-(E)-ylidene]-hydrazide 
• 77811-92-8 3-[1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-5-phenyl-1-{[1-phenyl-meth-(E)-ylidene]-amino}-1,3-dihydro-pyrrol-2-one 
• 77811-68-8 2-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-4-oxo-4-phenyl-butyric acid [1-phenyl-meth-(E)-ylidene]-hydrazide 
• 77811-70-2 2-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-4-oxo-4-phenyl-butyric acid [1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide 
• 77811-73-5 2-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-4-oxo-4-phenyl-butyric acid [(E)-3-phenyl-prop-2-en-(E)-ylidene]-hydrazide 
• 77811-72-4 2-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-4-oxo-4-phenyl-butyric acid [1-(4-dimethylamino-phenyl)-meth-(E)-ylidene]-hydrazide 
• 77811-69-9 2-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-4-oxo-4-phenyl-butyric acid [1-(2-hydroxy-phenyl)-meth-(E)-ylidene]-hydrazide 

Relevant academic research and scientific papers

Synthesis, cytotoxic activity, and tubulin polymerization inhibitory activity of new pyrrol-2(3H)-ones and pyridazin-3(2H)-ones

A series of new pyrrol-2(3H)-ones 4a-f and pyridazin-3(2H)-ones 7a-f were synthesized and characterized using different spectroscopic tools. Some of the tested compounds revealed moderate activity against 60 cell lines. The E form of the pyrrolones 4 show

Conversion of α-Arylidene-γ-phenyl-Δβ,γ-butenolides into Nitrogen Heterocycles

Treatment of α-arylidene-γ-phenyl-Δβ,γ-butenolides (I) with strong nucleophiles brings about opening of the γ-lactone ring with the formation of acyclic acid derivatives (II).The acid hydrazides (IIa-d) undergo facile condensation with carbonyl