134529-30-9Relevant academic research and scientific papers
Synthesis, cytotoxic activity, and tubulin polymerization inhibitory activity of new pyrrol-2(3H)-ones and pyridazin-3(2H)-ones
Abbas, Samar Hafez,Abuo-Rahma, Gamal El-Din A.A.,Abdel-Aziz, Mohamed,Aly, Omar M.,Beshr, Eman A.,Gamal-Eldeen, Amira M.
, p. 46 - 62 (2016/04/05)
A series of new pyrrol-2(3H)-ones 4a-f and pyridazin-3(2H)-ones 7a-f were synthesized and characterized using different spectroscopic tools. Some of the tested compounds revealed moderate activity against 60 cell lines. The E form of the pyrrolones 4 show
Palladium-catalyzed carbonylative coupling of aryl iodides and benzyl acetylenes to 3-alkylidenefuran-2-ones under mild conditions and its density functional theory modeling
Wu, Xiao-Feng,Jiao, Haijun,Neumann, Helfried,Beller, Matthias
, p. 16177 - 16185 (2013/02/22)
A general and efficient method for the palladium-catalyzed carbonylative coupling of aryl iodides to benzyl acetylenes has been developed. Various furanones have been prepared in excellent yields from their corresponding benzyl acetylenes at room temperat
A general cyclocarbonylation of aryl bromides and triflates with acetylenes: Palladium-catalyzed synthesis of 3-alkylidenefuran-2-ones
Wu, Xiao-Feng,Sundararaju, Basker,Anbarasan, Pazhamalai,Neumann, Helfried,Dixneuf, Pierre H.,Beller, Matthias
supporting information; experimental part, p. 8014 - 8017 (2011/09/14)
Making use of CO: An improved efficient synthesis of 5-aryl-3- alkylidenefuran-2-ones has been developed (see scheme). Starting from readily available (hetero)aryl bromides or aryl triflates and alkynes, furanones were produced in good yields through a do
Stereospecific Palladium(II)-Catalyzed Cyclocarbonylation of 3-Aryl-1-propynes and Iodoarenes of Acid Chlorides To Form (E)-3-Arylidenebutenolides
Huang, Yujin,Alper, Howard
, p. 4534 - 4536 (2007/10/02)
Iodoarenes react with 3-aryl-1-propynes and carbon monoxide, in the presence of palladium acetate and triphenylphosphine, to form (E)-arylidenebutenolides in 33-88percent isolated yields.The same product is formed by substitution of acid chloride for a io
