58024-06-9

Upstream product

• 6834-42-0 3-methoxyphenylacetic acid chloride 
• 352022-37-8 1-(6-methoxy-3,4-dihydro-naphthalen-1-yl)-2-(3-methoxy-phenyl)-ethanone 
• 70157-87-8 N'-(6-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)-4-methylbenzenesulfonohydrazide 
• 54173-10-3 (+/-)-2,8-dimethoxy-(4bc,10bc)-4b,5,6,10b,11,12-hexahydro-chrysene 

Relevant academic research and scientific papers

Synthesis and evaluation of hexahydrochrysene and tetrahydrobenzofluorene ligands for the estrogen receptor

To prepare novel estrogen receptor (ER) ligands, we have developed a facile approach to substituted hexahydrochrysene and tetrahydrobenzo[a]fluorene systems. Substituents, including basic side chains, were added to these systems, and their binding affinity to ERα and ERβ, and in some cases their transcriptional activity were evaluated.