58039-19-3

Upstream product

• 460-00-4 1-Bromo-4-fluorobenzene 
• 58039-18-2 7-fluoro-2-carbethoxy-1,2,3,4-tetrahydropyrrolo[3,4-b]indole 
• 823-85-8 4-fluorophenyhydrazine hydrochloride 
• 14891-10-2 ethyl-3-oxo-1-pyrrolidinecarboxylate 

Downstream Products

• 744145-76-4 7-fluoro-4-(p-fluorophenyl)-2-[3-(p-fluorobenzoyl)propyl]-1,2,3,4-tetrahydropyrrolo[3,4-b]indole 
• 343801-74-1 1-[7-Fluoro-4-(4-fluoro-phenyl)-3,4-dihydro-1H-pyrrolo[3,4-b]indol-2-yl]-2-phenyl-ethanone 
• 343836-01-1 1-[7-Fluoro-4-(4-fluoro-phenyl)-3,4-dihydro-1H-pyrrolo[3,4-b]indol-2-yl]-propan-1-one 
• 58039-20-6 7-fluoro-4-(4-fluorophenyl)-2-methyl-1,2,3,4-tetrahydropyrrolo<3,4-b>indole 
• 58039-25-1 7-fluoro-4-(4-fluorophenyl)-1,2,3,4-tetrahydropyrrolo<3,4-b>indole 

Relevant academic research and scientific papers

Process for preparing indole derivatives

Certain indole derivatives, and especially certain 1,2,3,4-tetrahydrocarbazoles, 1,2,3,4-tetrahydro-γ-carbolines and 1,2,3,4-tetrahydropyrrolo-[3,4-b]indoles are prepared by reacting the appropriate phenylhydrazine salt and ketone in the presence of a weakly basic solvent such as pyridine, quinoline, N,N-dimethylaniline, picoline or lutidine at a temperature in the range of about 50° to 180° C.

4-Aryl-1,2,3,4-tetrahydropyrrolo(3,4-b)indoles for treating schizophrenic manifestations

2-Substituted-4-aryl-1,2,3,4-tetrahydropyrrolo[3,4-b]-indoles, their use as tranquilizing agents and their preparation from 4-aryl-1,2,3,4-tetrahydropyrrolo[3,4-b]indoles.