58048-28-5

Basic information

• Product Name: (3aS,4S,6R,6aR)-6-(6-amino-9H-purin-9-yl)-N-cyclopropyl-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carboxamide (non-preferred name)
• CAS NO: 58048-28-5
• Molecular Formula: C₁₆H₂₀N₆O₄
• Molecular Weight: 360.3678
• Mol File: 58048-28-5.mol
• Article Data: 4

Chemical Properties

• Density: 1.85g/cm³
• Refractive Index: 1.849
• CAS DataBase Reference: (3aS,4S,6R,6aR)-6-(6-amino-9H-purin-9-yl)-N-cyclopropyl-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carboxamide (non-preferred name)(CAS DataBase Reference)
• NIST Chemistry Reference: (3aS,4S,6R,6aR)-6-(6-amino-9H-purin-9-yl)-N-cyclopropyl-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carboxamide (non-preferred name)(58048-28-5)
• EPA Substance Registry System: (3aS,4S,6R,6aR)-6-(6-amino-9H-purin-9-yl)-N-cyclopropyl-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carboxamide (non-preferred name)(58048-28-5)

Safety Data

• Hazardous Substances Data: 58048-28-5(Hazardous Substances Data)

Upstream product

• 159647-45-7 (3aS,4S,6R,6aR)-6-(6-Amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid 4-nitro-phenyl ester 
• 765-30-0 Cyclopropylamine 
• 19234-66-3 2',3'-isopropylideneadenosine-5'-carboxylic acid 
• 39491-49-1 2',3'-O-isopropylideneadenosine-5'-carbonyl chloride 

Relevant articles and documents

Nucleosides and nucleotides. 200. Reinvestigation of 5′-N-ethylcarboxamidoadenosine derivatives: Structure-activity relationships for P3 purinoceptor-like proteins

The non-P1 and non-P2 muscle relaxant effect of ATP in rabbit thoracic aorta has recently been attributed to a putative P3 purinoceptor, which is activated by either adenosine or ATP. Since the physiological roles of this

Modification of the 5' Position of Purine Nucleosides. 2. Synthesis and Some Cardiovascular Properties of Adenosine-5'-(N-substituted)carboxamides

We have shown previously that the esters of adenosine-5'-carboxylic acid (10) represent a new class of potent nontoxic coronary vasodilators.For example, the ethyl ester (12), which is active by an intraduodenal or intravenous route in dogs, causes a larg