58058-51-8

Basic information

• Product Name: 8-methyl-2-phenylquinazoline
• Synonyms: 8-methyl-2-phenylquinazoline
• CAS NO: 58058-51-8
• Molecular Weight: 220.274
• Mol File: 58058-51-8.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 8-methyl-2-phenylquinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 8-methyl-2-phenylquinazoline(58058-51-8)
• EPA Substance Registry System: 8-methyl-2-phenylquinazoline(58058-51-8)

Safety Data

• Hazardous Substances Data: 58058-51-8(Hazardous Substances Data)

Upstream product

• 57772-50-6 2-amino-3-methylbenzyl alcohol 
• 100-52-7 benzaldehyde 
• 100-47-0 benzonitrile 
• 50-00-0 formaldehyd 
• 57327-73-8 (Z)-N'-(o-tolyl)benzimidamide 
• 87-62-7 2,6-dimethylaniline 
• 16239-27-3 N-(2,6-dimethylphenyl)benzimidamide 
• 100-46-9 benzylamine 

Relevant articles and documents

BTP-Rh@g-C3N4 as an efficient recyclable catalyst for dehydrogenation and borrowing hydrogen reactions

Highly active catalysts play an important role in modern catalysis. A novel and efficient ligand benzotriazole-pyrimidine (BTP) and the corresponding rhodium composite on C3N4 were successfully synthesized. The resulting rhodium composite was fully characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), x-ray diffraction (XRD), thermogravimetric analysis (TGA), and x-ray photoelectron spectroscopy (XPS). The obtained composite exhibited good catalytic activity and good recovery performance in the synthesis of quinoxaline from 2-aminobenzyl alcohol and benzonitrile, and more than 20 quinoxalines were obtained in good yields. Additionally, it also showed that rhodium composite could achieved good catalytic performance in the synthesis of functionalized ketone through borrowing hydrogen strategy.

A cobalt-catalyzed method for synthesizing quinoline and quinazoline compounds

The present invention discloses a cobalt-catalyzed synthesis of quinoline and quinazoline compounds, by a benzene compound with amino and hydroxyl groups or benzonitrile compounds as raw materials, in the presence of a catalyst and a base by a receptor-fr

NNN pincer Ru(II)-catalyzed dehydrogenative coupling of 2-aminoarylmethanols with nitriles for the construction of quinazolines

An efficient NNN pincer Ru(II)-catalyzed preparation of quinazolines via acceptorless dehydrogenative strategy has been developed. Under the optimized conditions, a broad range of substituted o-aminobenzyl alcohols and (hetero)aryl or alkyl nitriles were well tolerated to afford various 2-substituted quinazolines in high yields. Subsequently, a set of control experiments have been performed to elucidate the reaction mechanism, which underwent alcohol oxidation, nitrile hydration, and cyclocondensation steps. The current protocol is featured with several advantages, such as environmental benignity, operational simplicity, broad substrate scope (compatible with aliphatic nitriles, up to 87% yield), and short reaction time (mostly in 2 h).