58058-52-9Relevant academic research and scientific papers
Copper-Catalyzed Multicomponent Domino Reaction of 2-Bromoaldehydes, Benzylamines, and Sodium Azide for the Assembly of Quinazoline Derivatives
Xu, Cheng,Jia, Feng-Cheng,Zhou, Zhi-Wen,Zheng, Si-Jie,Li, Han,Wu, An-Xin
, p. 3000 - 3006 (2016)
An efficient three-component domino reaction of 2-bromoaldehydes, benzylamines, and sodium azide has been developed for the synthesis of quinazoline derivatives. This domino process involves copper-catalyzed SNAr, oxidation/cyclization, and denitrogenation sequences. The mild catalytic system enabled the effective construction of three C-N bonds in one operation.
Lewis acid-catalyzed 2-arylquinazoline formation from: N ′-arylbenzimidamides and paraformaldehyde
Cheng, Xiufang,Wang, Huamin,Xiao, Fuhong,Deng, Guo-Jun
supporting information, p. 5773 - 5776 (2016/11/06)
An efficient procedure for the synthesis of 2-arylquinazolines from N′-arylbenzimidamides has been developed under transition-metal-free conditions. In this process, stable and low-toxicity paraformaldehyde was used as the carbon source. A broad range of
