581065-74-9

Upstream product

• 581065-57-8 4,4,5,5-tetramethyl-2-[3-(2-(1-piperidinyl)ethyloxy)phenyl]-[1,3,2]-dioxaborolane 
• 581065-73-8 2,7-dimethoxy-10-oxo-10H-benzo[b]indeno[2,1-d]thiophen-9-yl trifluoromethanesulfonate 
• 591-20-8 3-Bromophenol 
• 2008-75-5 N-chloroethylpiperidine hydrochloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 613-45-6 2,4-Dimethoxybenzaldehyde 
• 185415-33-2 2-N,N-Dimethylamino-4,6-dimethoxybenzothiophene 
• 346592-24-3 4,6-dimethoxy-2,3-dihydrobenzo[b]thiophen-2-one 
• 202337-50-6 N,N-dimethyl 2-(2,4-dimethoxyphenyl)-2-hydroxyethanethioamide 
• 554430-68-1 1-[2-(3-bromophenoxy)ethyl]piperidine 
• 581065-72-7 9-hydroxy-2,7-dimethoxy-10H-benzo[b]indeno[2,1-d]thiophen-10-one 
• 581065-71-6 2,7,9-trimethoxy-10H-benzo[b]indeno[2,1-d]thiophen-10-one 
• 581065-55-6 N,N-diethyl 4,6-dimethoxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b]thiophene-3-carboxamide 
• 581065-70-5 N,N-diethyl 4-hydroxy-6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophene-3-carboxamide 

Relevant academic research and scientific papers

Synthesis of constrained raloxifene analogues by complementary use of Friedel-Crafts and directed remote metalation reactions

New constrained heterocyclic analogues, 2a,b and 3, of Raloxifene (1) have been prepared by complementary Directed remote Metalation (DreM)/Friedel-Crafts cyclization approaches. Utilization of a benzylidene-thiolactone rearrangement was successfully impl