58116-20-4

Upstream product

• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 140-88-5 ethyl acrylate 
• 3674-13-3 2,3-dibromopropionic acid ethyl ester 
• 68820-82-6 (2R)-1[(R)-α-methylbenzyl]-2-aziridinecarboxylate ethyl ester 
• 68820-72-4 (2S)-1-[(R)-α-methylbenzyl]-2-aziridinecarboxylate ethyl ester 

Downstream Products

• 174836-08-9 N-(R)-α-methylbenzyl-1,1-dideuterio-3-aminopropan-1-ol 
• 36940-65-5 (S)-Ethyl 3-(1-phenylethylamino)propanoate 

Relevant academic research and scientific papers

Stereospecific synthesis of tetradeuterated (R)- and (S)-ifosfamide

The tetradeuterated analogues of (R)- and (S)-ifosfamide [(S)- and (R)-2-(2-chloro-2,2-dideuterioethyl)amino-3-(2-chloroethyl)-6,6-dideuterio -tetrahydro-2H-1,3,2-oxazaphosphorin-2-oxide, (S)- and (R)-1-d4] were synthesized by modification of a

Regiospecific reductive ring cleavage of N-substituted aziridine-2-carboxylates and An aziridine-2-methanol via catalytic hydrogenation using Pd as a catalyst

Regiospecific reductive ring cleavage was accomplished in the reaction of N-α-methylbenzyl substituted aziridine-2-carboxylate and aziridine-2-methanol under a catalytic hydrogenation condition. The regiospecificity was determined by the substituent at C-