58123-69-6

Usage

Uses

Used in Organic Synthesis:
3-Bromo-4-Cyanobenzoic Acid is used as an intermediate in organic synthesis for the production of various chemical compounds. Its unique structure and properties make it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Bromo-4-Cyanobenzoic Acid is used as a building block for the development of new drugs. Its presence of bromine, cyanide, and carboxylic acid groups allows for the creation of diverse molecular structures with potential therapeutic applications.
Used in Agrochemical Industry:
3-Bromo-4-Cyanobenzoic Acid is also employed in the agrochemical industry as a precursor for the synthesis of pesticides and other crop protection agents. Its versatility in chemical reactions enables the production of effective and targeted agrochemical products.
Safety and Handling:
Due to its potential hazards, 3-Bromo-4-Cyanobenzoic Acid requires a risk and safety assessment. It is considered harmful if swallowed or if it comes into contact with skin or eyes, and can cause respiratory irritation. Therefore, it must be handled and packed according to EPA guidelines to ensure the safety of workers and the environment.

Upstream product

• 42872-73-1 4-methyl-2-bromobenzonitrile 
• 106896-49-5 methyl 4-amino-3-bromobenzoate 
• 942598-44-9 methyl 3-bromo-4-cyanobenzoate 

Downstream Products

• 1008520-70-4 2-Bromo-4-(3-methoxy-5,5-dimethyl-2-oxo-cyclohex-3-enecarbonyl)-benzonitrile 
• 1008519-98-9 2-Bromo-4-(1,5,5-trimethyl-7-oxo-4,5,6,7-tetrahydro-1H-indazol-3-yl)-benzonitrile 
• 1008520-00-0 2-(Tetrahydro-pyran-4-ylamino)-4-(1,5,5-trimethyl-7-oxo-4,5,6,7-tetrahydro-1H-indazol-3-yl)-benzonitrile 
• 1008520-02-2 2-(Tetrahydro-pyran-4-ylamino)-4-(1,5,5-trimethyl-7-oxo-4,5,6,7-tetrahydro-1H-indazol-3-yl)-benzamide 
• 1609540-90-0 4-(((tert-butyldimethylsilyl)oxy)methyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile 
• 1609540-86-4 4-(((tert-butyldimethylsilyl)oxy)methyl)-2-formylbenzonitrile 
• 1609540-79-5 5-((tert-butyldimethylsilyloxy)methyl)-2-cyanobenzoic acid 
• 90110-97-7 2-bromo-4-(hydroxymethyl)benzonitrile 
• 1609540-82-0 2-bromo-4-((tert-butyldimethylsilyloxy)methyl)benzonitrile 

Relevant academic research and scientific papers

Light and oxygen-enabled sodium trifluoromethanesulfinate-mediated selective oxidation of C-H bonds

Visible light-induced organic reactions are important chemical transformations in organic chemistry, and their efficiency highly depends on suitable photocatalysts. However, the commonly used photocatalysts are precious transition-metal complexes and elaborate organic dyes, which hamper large-scale production due to high cost. Here, for the first time, we report a novel strategy: light and oxygen-enabled sodium trifluoromethanesulfinate-mediated selective oxidation of C-H bonds, allowing high-value-added aromatic ketones and carboxylic acids to be easily prepared in high-to-excellent yields using readily available alkyl arenes, methyl arenes and aldehydes as materials. The mechanistic investigations showed that the treatment of inexpensive and readily available sodium trifluoromethanesulfinate with oxygen under irradiation of light could in situ form a pentacoordinate sulfide intermediate as an efficient photosensitizer. The method represents a highly efficient, economical and environmentally friendly strategy, and the light and oxygen-enabled sodium trifluoromethanesulfinate photocatalytic system represents a breakthrough in photochemistry. This journal is

Benzene, Pyridine, and Pyridazine Derivatives

Disclosed are compounds and pharmaceutically acceptable salts of Formula I wherein A, Q1, Q2, Q3, R31, and R41 are as defined herein. Compounds of Formula I are useful in the treatment of diseases and