58124-28-0 Usage
Uses
Used in Pharmaceutical Industry:
2-AMINO-4-CYCLOPROPYLTHIOPHENE-3-CARBONITRILE is used as a reagent for the synthesis of a novel class of CCR3 modulators. These modulators have potential therapeutic applications in the treatment of weight disorders and cognitive disorders. 2-AMINO-4-CYCLOPROPYLTHIOPHENE-3-CARBONITRILE plays a crucial role in the development of these modulators by providing a structural framework that can be further modified and optimized for specific therapeutic effects.
Check Digit Verification of cas no
The CAS Registry Mumber 58124-28-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,1,2 and 4 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 58124-28:
(7*5)+(6*8)+(5*1)+(4*2)+(3*4)+(2*2)+(1*8)=120
120 % 10 = 0
So 58124-28-0 is a valid CAS Registry Number.
58124-28-0Relevant academic research and scientific papers
SYNTHESIS AND NITRATION OF SOME 4-CYCLOPROPYL- AND 4-(p-CYCLOPROPYLPHENYL)-2-AMINOTHIOPHENES
Surikova, T. P.,Zakharova, V. D.,Mochalov, S. S.,Shabarov, Yu. S.
, p. 860 - 864 (2007/10/02)
A number of cyclopropyl-substituted crotononitriles have been synthesized by a Knoevenagel condensation. Reaction of these compounds with sulfur in the presence of a base gives substituted 4-cyclopropyl- and 4-cyclopropylphenyl-2-aminothiophenes, while nitration of some acetylaminothiophenes with acetyl nitrate in acetic anhydride at low temperature gives the corresponding nitro derivatives.
