58139-10-9

Usage

InChI:InChI=1/C13H15ClO/c14-12-9-5-4-8-11(12)13(15)10-6-2-1-3-7-10/h4-5,8-10H,1-3,6-7H2

Upstream product

• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 2719-27-9 cyclohexanylcarbonyl chloride 
• 1268102-42-6 1-(2-chlorophenyl)cyclohexanecarbaldehyde 
• 2856-63-5 2-Chlorophenylacetonitrile 
• 106795-73-7 1-(2-chlorophenyl)cyclohexane-1-carbonitrile 
• 873-32-5 2-Chlorobenzonitrile 
• 931-50-0 cyclohexylmagnesium bromide 

Downstream Products

• 64436-55-1 α-(2-chlorophenyl)-α-cyclohexyl-2-pyridinemethanol 
• 64436-47-1 α-(2-Chlorophenyl)-α-cyclohexyl-4-pyridinemethanol 
• 64436-39-1 α-(2-chlorophenyl)-α-cyclohexyl-2-pyridinemethane 

Relevant academic research and scientific papers

A study about the synthesis of seven-membered-ring analogues of ketamine

Synthesis of seven-membered ring analogues of ketamine was studied with two strategies. In the first approach a sequence of five reactions was used which previously applied for ketamine synthesis. This strategy led to formation of 1-[(2-chlorophenyl)(methylimino)methyl]cyclohexan-1-ol as a precursor for the target molecule. In the second approach, we have designed and attempted to synthesize a new analogue of ketamine applying challenging reactions such as ring expansion and selective bromination. The result of this route is synthesis of some interesting compounds such as 6-phenyl-1-oxa-4-thiaspiro[4.6]undecane, 3-bromo-6-phenyl-1-oxa-4-thiaspiro[4.6]undecane and 2,7-dibromo-2-phenylcycloheptanone.

Fe-catalyzed regiodivergent [1,2]-shift of α-aryl aldehydes

An Fe-catalyzed conversion of aldehydes to ketones via [1,2]-shift has been developed. This skeletal rearrangement shows a wide substrate scope and chemoselectivity profile while exhibiting an excellent [1,2]-aryl or [1,2]-alkyl shift selectivity that is easily switched by electronic effects.

Insertion of arynes into carbon-halogen σ-bonds: Regioselective acylation of aromatic rings

Arynes were found to insert into carbon-halogen σ-bonds of various acid halides, enabling acyl and halogen moieties to be introduced simultaneously into adjacent positions of aromatic rings. The Royal Society of Chemistry.

Method of regulating the growth of aquatic weeds with pyridine derivatives

A method of regulating the growth of submerged and floating aquatic weeds which comprises adding a 2- or 4-substituted pyridinemethane or pyridinemethanol to a body of water containing the submerged and floating aquatic weeds to be regulated, in quantities sufficient to regulate the growth of the submerged and floating aquatic weeds therein. The disclosure also relates to novel compositions for carrying out the method.