58151-87-4Relevant academic research and scientific papers
Regioselective O2′,O3′-deacetylations of peracetylated ribonucleosides by using tetra-n-butylammonium fluoride
Babu Kumar, Arun,Manetsch, Roman
supporting information, p. 3551 - 3555 (2014/06/23)
A robust, mild, and highly regioselective deacetylation of 1,2-diol diacetates in the presence of other acetate functions was achieved by using tetra-n-butylammonium fluoride. This method provided a single-step route to access O5′-acetyl ribonucleosides, a key intermediate in the synthesis of biomedically important nucleosides and nucleotides. Moreover, it offered the general applicability of a non-enzymatic method for the selective deacetylation of peracetylated 2′-deoxyribonucleosides. Its synthetic utility was further demonstrated by the synthesis of molecules of biomedical interest by using this particular deacetylation reaction. Copyright
1-(β,-D-ribofuranosyl)-1,2,4-triazole acid esters
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, (2008/06/13)
Phosphate and carboxylic acid esters of 1-(β-D-ribofuranosyl)-1,2,4-triazoles are prepared by a variety of methods and their antiviral activity reported.
