58154-01-1

Upstream product

• 108-90-7 chlorobenzene 
• 3946-29-0 3,4'-Dichloropropiophenone 
• 106-47-8 4-chloro-aniline 
• 1798-83-0 1-(4-chlorophenyl)-3-dimethylamino-propan-1-one hydrochloride 

Downstream Products

• 95886-27-4 2-Chloro-3,6-bis-(4-chloro-phenyl)-3,4-dihydro-[1,3,2]oxazaphosphinine 2-oxide 

Relevant academic research and scientific papers

I2-Promoted Intramolecular Oxidative Cyclization of Butenyl Anilines: A Facile Route to Benzo[b]azepines

A metal-free approach for the synthesis of seven-membered N-heterocycles has been developed by the I2-promoted intramolecular cross-coupling/annulation of butenyl anilines. This cyclization reaction involves C?H activation and C?C bond formation and exhibits good functional group tolerance. A series of benzo[b]azepine derivatives are obtained in moderate to good yields.

Synthesis of Heterocyclic Compounds: Part XXVIII - Potential Antileukemic Agents from 3,4-Dihydro-1,3,2-oxazaphosphorin-2-oxides

Some 3,6-diaryl-2-chloro-3,4-dihydro-1,3,2-oxazaphosphorin-2-oxides (4a-q, 6a-e and 7a, b) have been synthesised and tested for their anti-leukemic activity.