58161-29-8Relevant academic research and scientific papers
Monoquaternary neuromuscular blocking agents based on 1 tetralone and 1 indanone
Biggs,Casy,Chu,Coutts
, p. 472 - 475 (1976)
The preparation of three isomeric 1 tetralone hydrazones and three isomeric 1 indanone hydrazones possessing a single quaternary ammonium center is described. Several of the compounds possessed significant neuromuscular blocking activity, and two approached suxamethonium in potency. 1H NMR evidence obtained from a study of the N,N dimethylhydrazones indicated that the hydrazones adopted an E configuration in solution.
