58161-31-2 Usage
Uses
Used in Pharmaceutical Industry:
8-Nitro-1-tetralone is used as a synthetic reagent for the introduction of nitro groups into other compounds. Its application is particularly relevant in the development of new pharmaceuticals, where the nitro group can be a key structural element in the synthesis of various drug molecules.
Used in Materials Science:
In the field of materials science, 8-Nitro-1-tetralone serves as a reagent to modify the properties of materials by incorporating nitro groups. This can lead to the creation of novel materials with enhanced characteristics, such as improved stability or reactivity, which can be beneficial in a range of applications.
Check Digit Verification of cas no
The CAS Registry Mumber 58161-31-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,1,6 and 1 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 58161-31:
(7*5)+(6*8)+(5*1)+(4*6)+(3*1)+(2*3)+(1*1)=122
122 % 10 = 2
So 58161-31-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H9NO3/c12-9-6-2-4-7-3-1-5-8(10(7)9)11(13)14/h1,3,5H,2,4,6H2
58161-31-2Relevant academic research and scientific papers
Palladium-catalyzed chelation-assisted aromatic C-H nitration: Regiospecific synthesis of nitroarenes free from the effect of the orientation rules
Zhang, Wei,Lou, Shaojie,Liu, Yunkui,Xu, Zhenyuan
, p. 5932 - 5948 (2013/07/26)
A palladium-catalyzed chelation-assisted ortho-nitration of aryl C-H bond is described. A range of azaarenes such as 2-arylquinoxalines, pyridines, quinoline, and pyrazoles were nitrated with excellent chemo- and regioselectivity. Using the O-methyl oximyl group as a removable directing group, the regiospecific synthesis of a variety of o-nitro aryl ketones was achieved starting from aryl ketones via a three-step process involving the Pd-catalyzed ipso-nitration of C-H bond as a key step. Mechanistic investigations support a silver-mediated radical mechanism involving Pd((II/III) and/or Pd(II/IV) catalytic cycles under oxidizing conditions.
