58169-12-3Relevant academic research and scientific papers
Eco-friendly synthesis of α-aminonitriles from ketones in PEG-400 medium using potassium Hexacyanoferrate(II) as cyanide source
Hu, Xiaochun,Ma, Yuanhong,Li, Zheng
experimental part, p. 70 - 74 (2012/04/17)
An efficient method for the synthesis of α-aminonitriles via one-pot three-component condensation of ketones, amines and potassium hexacyanoferrate(II) using benzoyl chloride as a promoter and PEG-400 as a reaction medium was described. This protocol has
One-pot three-component synthesis of α-aminonitriles using potassium hexacyanoferrate(II) as an eco-friendly cyanide source
Li, Zheng,Ma, Yuanhong,Xu, Jun,Shi, Jinghong,Cai, Hongfang
experimental part, p. 3922 - 3926 (2010/08/20)
An efficient and environmentally friendly method has been developed for the synthesis of α-aminonitriles via one-pot three-component condensation of carbonyl compounds, amines, and potassium hexacyanoferrate(II) in the presence of benzoyl chloride as a promoter. This protocol has the features of use of eco-friendly cyanide source, high yield, and simple work-up procedure.
