581782-99-2Relevant academic research and scientific papers
De novo asymmetric bio- and chemocatalytic synthesis of saccharides - Stereoselective formal O-glycoside bond formation using palladium catalysis
Comely, Alex C.,Eelkema, Rienk,Minnaard, Adriaan J.,Feringa, Ben L.
, p. 8714 - 8715 (2007/10/03)
A novel integrated bio- and chemocatalytic approach to the de novo catalytic asymmetric synthesis of saccharides has been developed. Acetoxypyranones obtained enantiopure by enzymatic resolution have been shown to undergo highly stereoselective palladium-catalyzed formal O-glycoside bond formation. The combination of these protocols can be applied to the iterative asymmetric catalytic synthesis of saccharides. Copyright
