58186-01-9

Usage

Uses

Used in Pharmaceutical Synthesis:
6-(3-carboxypropyl)-2,3-diMethoxy-5-Methyl-1,4-benzoquinone is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic benefits.
Used in Organic Chemistry:
As an intermediate in organic chemistry, 6-(3-carboxypropyl)-2,3-diMethoxy-5-Methyl-1,4-benzoquinone plays a crucial role in the formation of complex organic molecules, contributing to the advancement of chemical research and the creation of novel compounds.
Used in Medical Research:
6-(3-carboxypropyl)-2,3-diMethoxy-5-Methyl-1,4-benzoquinone is being studied for its potential medical applications, particularly in the treatment of neurological disorders. Its biological activity suggests that it may have a positive impact on the management or treatment of such conditions.
Used in Cancer Research:
6-(3-carboxypropyl)-2,3-diMethoxy-5-Methyl-1,4-benzoquinone is also being explored for its potential role in cancer treatment. Its biological activity indicates that it may contribute to the development of new therapeutic strategies against various types of cancer.

Upstream product

• 58185-87-8 4-(2'-hydroxy-3',4'-dimethoxy-6'-methylphenyl)butyric acid 
• 6443-69-2 3,4,5-trimethoxytoluene 
• 58185-81-2 3-(2'-hydroxy-3',4'-dimethoxy-6'-methylbenzoyl)propionic acid 
• 110-94-1 1,5-pentanedioic acid 
• 605-94-7 2,3-Dimethoxy-5-methyl-1,4-benzoquinone 

Downstream Products

• 88191-47-3 4-(4,5-Dimethoxy-2-methyl-3,6-dioxo-cyclohexa-1,4-dienyl)-butyric acid methyl ester 
• 89048-29-3 4-(2,5-diacetoxy-3,4-dimethoxy-6-methylphenyl)butyric acid 
• 58186-23-5 6-(3-ethoxycarbonylpropyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone 
• 95233-52-6 2,5-dihydroxy-3,4-dimethoxy-6-methyl-benzenebutanoic acid 
• 89048-63-5 2-(4-Dimethylamino-butyl)-5,6-dimethoxy-3-methyl-[1,4]benzoquinone 
• 95233-53-7 C₁₄H₁₉O₉S^(1-)*Na⁽¹⁺⁾ 
• 95233-54-8 sodium salt of 2,3-dimethoxy-6-(3-methoxycarbonylpropyl)-5-methylhydroquinone 4-sulfate 
• 103993-51-7 Sodium; 4-(3-hydroxy-4,5-dimethoxy-2-methyl-6-sulfooxy-phenyl)-butyrate 
• 95233-63-9 6-(3-carboxypropyl)-2,3-dimethoxy-5-methylhydroquinone 4-sulfate, dipotassium salt 
• 89048-31-7 4-(2,5-diacetoxy-3,4-dimethoxy-6-methylphenyl)-N,N-dimethylbutanamide 
• 89048-30-6 [6-(3-chloroformylpropyl)-2,3-dimethoxy-5-methylhydroquinone]diacetate 
• 95233-64-0 2,3-dimethoxy-6-(3-methoxycarbonylpropyl)-5-methylhydroquinone 
• 84166-52-9 6-(3-benzyloxycarbonylpropyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone 

Relevant academic research and scientific papers

Bioactivity profiles of cytoprotective short-chain quinones

Short-chain quinones (SCQs) have been investigated as potential therapeutic candidates against mitochondrial dysfunction, which was largely thought to be associated with the reversible redox characteristics of their active quinone core. We recently reported a library of SCQs, some of which showed potent cytoprotective activity against the mitochondrial complex I inhibitor rotenone in the human hepatocarcinoma cell line HepG2. To better characterize the cytoprotection of SCQs at a molecular level, a bioactivity profile for 103 SCQs with different compound chemistries was generated that included metabolism related markers, redox activity, expression of cytoprotective proteins and oxidative damage. Of all the tested endpoints, a positive correlation with cytoprotection by SCQs in the presence of rotenone was only observed for the NAD(P)H:quinone oxidoreductase 1 (NQO1)-dependent reduction of SCQs, which also correlated with an acute rescue of ATP levels. The results of this study suggest an unexpected mode of action for SCQs that appears to involve a modification of NQO1-dependent signaling rather than a protective effect by the reduced quinone itself. This finding presents a new selection strategy to identify and develop the most promising compounds towards their clinical use.

Aralkyl carboxylic acid compounds

Novel compounds of the formulae STR1 wherein R represents lower alkyl or lower alkoxy, A represents --CH2 --, --CO-- or STR2 n represents an integer of 1 to 8, X represents hydrogen or hydroxyl which may be protected and Y represents hydroxyl which may be protected, and their esters show an excellent action on the lysosomal membranes of cells, and exhibit excellent pharmacological activities such as physiologic host defense control activity, especially immuno-potentiating activity.