58226-87-2Relevant academic research and scientific papers
Mixed alkoxy/hydroxy 1,8-naphthalimides: expanded fluorescence colour palette and: In vitro bioactivity
Acharya, Rameshwor,Ashton, Trent D.,Bell, Toby D. M.,Cox, Rosalind P.,Feng, Zikai,Gueven, Nuri,Pfeffer, Frederick M.,Rudebeck, Elley E.
, p. 6866 - 6869 (2020)
An efficient and functional group tolerant route to access hydroxy 1,8-naphthalimides has been used to synthesise a range of mono- and disubstituted hydroxy-1,8-naphthalimides with fluorescence emissions covering the visible spectrum. The dialkoxy substit
METHODS AND COMPOSITIONS FOR TREATING BETA-THALASSEMIA AND SICKLE CELL DISEASE
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Paragraph 0221; 0222; 0234, (2016/05/19)
Compounds, pharmaceutical compositions, and methods for treating anemia β-thalassemia anemia or sickle cell anemia.
Methods and compositions for treating beta-thalassemia and sickle cell disease
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Paragraph 0289; 0290; 0291; 0292; 0315; 0316, (2016/10/08)
Compounds, pharmaceutical compositions, and methods for treating anemia beta-thalassemia anemia or sickle cell anemia are disclosed.
The heterocyclic ring of 4-substituted-1,8-naphthalimides is NOT inert to nucleophilic attack, contrary to earlier reports
McKenney, Ryan K.,Groess, Leah L.,Kopidlansky, Kyle M.,Dunkle, Kelsey L.,Lewis, David E.
, p. 4390 - 4396 (2013/08/23)
The heterocyclic ring of N-aryl-4-chloro-1,8-naphthalimides, reported to be resistant to nucleophilic attack, reacts with primary amine nucleophiles at room temperature to give 4-chloro-N-alkyl-1,8-naphthalimides. The reaction is first order in the naphth
