582307-06-0 Usage
Uses
Used in Medicinal Chemistry:
3,5-Difluoro-benzamidine is used as a key intermediate in the synthesis of various pharmaceuticals for the development of potential treatments for different diseases. Its unique structure allows for the design of novel drug candidates with improved pharmacological properties.
Used in Drug Discovery:
3,5-Difluoro-benzamidine serves as a valuable tool in drug discovery, enabling researchers to explore its potential as a therapeutic agent or as a component of drug candidates. Its presence in compounds can modulate biological activities and target specific pathways, contributing to the advancement of new treatments.
Used in Chemical Reactions:
3,5-Difluoro-benzamidine is utilized as a reagent in chemical reactions to introduce the benzamidine functionality into molecules. This is crucial for the development of potential drug candidates, as the benzamidine group can form strong coordination with metal ions and interact with various biological targets, enhancing the compound's therapeutic potential.
Used in Organic Synthesis:
In the field of organic synthesis, 3,5-difluoro-benzamidine is employed as a building block for the construction of complex organic molecules. Its fluorinated benzene ring and benzamidine group provide opportunities for further functionalization and modification, leading to the creation of diverse chemical entities with potential applications in various industries.
Overall, 3,5-difluoro-benzamidine is a versatile and valuable compound in the fields of medicinal chemistry, drug discovery, and organic synthesis, offering numerous applications and opportunities for the development of novel therapeutic agents and chemical entities.
Check Digit Verification of cas no
The CAS Registry Mumber 582307-06-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,8,2,3,0 and 7 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 582307-06:
(8*5)+(7*8)+(6*2)+(5*3)+(4*0)+(3*7)+(2*0)+(1*6)=150
150 % 10 = 0
So 582307-06-0 is a valid CAS Registry Number.
InChI:InChI=1S/C7H6F2N2/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3H,(H3,10,11)
582307-06-0Relevant articles and documents
Reaction of arylhalodiazirines with thiophenoxide: A redox process
Creary, Xavier,Sky, Anthony F.,Phillips, Gillian,Alonso, David E.
, p. 7584 - 7592 (2007/10/02)
Phenylbromodiazirine reacts with thiophenoxide ion in methanol to give benzonitrile, benzamidine, ammonia, and diphenyl disulfide. The reaction is general for arylhalodiazirines, with electron-withdrawing groups on the aromatic ring exerting a small rate-enhancing effect. Three potential mechanisms are suggested for this redox process. These mechanisms include an N-sulfenylated diazirine, a diazirinyl radical, and a diazirinyl anion. Ring opening of these intermediates and subsequent transformations would lead to benzonitriles, benzamidine, and ammonia. A key intermediate in these transformations is PhSNH2, 32. This intermediate has been independently generated and found to rapidly convert to ammonia and diphenyl disulfide under the reaction conditions. Another proposed intermediate, N-(phenylthio)benzamidine, 38, has also been independently generated and subjected to the reaction conditions, where benzamidine and more diphenyl disulfide result. Theoretical calculations suggest the existence of isomeric diazirinyl anions. In addition to a diazirinyl ion with charge essentially on carbon, there is also an allylic-type ion with charge on the two nitrogen atoms. Single-electron reduction of a diazirinyl radical necessarily leads to a nitrogen-centered diazirinyl anion. Conversion of this anion to the carbon-centered diazirinyl anion is a forbidden process. These theoretical studies suggest that the diazirinyl anion may be a viable intermediate in solution.
