582308-13-2

Upstream product

• 57783-76-3 benzyl 2,3,4-tri-O-benzyl-α-D-mannopyranoside 
• 100-39-0 benzyl bromide 
• 1222709-77-4 benzyl 6-O-tetra-butyldiphenylsilyl-2,3,4-O-tribenzyl-α-D-mannopyranoside 
• 1554004-68-0 benzyl 2,3,4-O-tribenzyl-6,7-dideoxy-α-D-hept-6-enopyranoside 
• 106445-56-1 benzyl 2,3,4-tri-O-benzyl-α-D-glycero-D-manno-heptopyranoside 
• 1554004-75-9 benzyl 7-O-tetra-butyldiphenylsilyl-2,3,4-O-tri-benzyl-D-glycero-α-D-mannoheptopyranoside 
• 114894-82-5 benzyl 6-O-tetra-butyldiphenylsilyl-α-D-mannopyranoside 
• 15548-45-5 (2S,3S,4S,5S,6R)-2-benzyloxy-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol 
• 530-26-7 D-Mannose 
• 1554004-98-6 benzyl 7-O-tetra-butyldiphenylsilyl-6-O-(phenorythiocarbonyl)-2,3,4-O-tri-benzyl-D-glycero-α-D-mannoheptopyranoside 
• 102046-36-6 (2S,3S,4S,5S,6S)-3,4,5,6-tetrabenzyloxytetrahydropyran-2-carbaldehyde 
• 1554005-00-3 benzyl 7-O-tetra-butyldiphenylsilyl-2,3,4-O-tri-benzyl-6-deoxy-glycero-α-D-mannoheptopyranoside 
• 582308-12-1 benzyl 6-deoxy-6-(2'-dithianyl)-2,3,4-tri-O-benzyl-α-D-mannopyranoside 

Relevant academic research and scientific papers

Chemoenzymatic synthesis of ADP-d-glycero-β-d-manno-heptose and study of the substrate specificity of HldE

An efficient one-pot three enzymes strategy for chemoenzymatic synthesis of ADP-d-glycero-β-d-manno-heptose (ADP-d, d-heptose) was reported using chemically synthesized d, d-heptose-7-phosphate and the ADP-d, d-heptose biosynthetic enzymes HldE and GmhB M

A convenient synthetic route to mannose 6-phosphonate-cholesteryl conjugate

The synthesis of mannose 6-phosphonate-based glycolipid was discussed. The synthesis involved a one-carbon chain elongation at the 6-position of mannose, followed by phosphonation, using tris(trimethylsilyl) phosphite. The final step of synthesis involved an Arbuzov reaction between the alkyl bromide derivative and tris(trimethylsilyl) phosphite, followed by deprotection of the acetate under Zemplen conditions.