58249-69-7

Usage

Uses

Used in Pharmaceutical Industry:
Benzothiazole, 5,6-dimethoxy(9CI) is used as a chemical intermediate for the synthesis of various pharmaceuticals, leveraging its unique structure and properties to contribute to the development of new drugs with potential therapeutic applications.
Used in Dye Industry:
In the dye industry, Benzothiazole, 5,6-dimethoxy(9CI) is utilized as a precursor in the production of dyes, taking advantage of its chemical characteristics to create colorants with specific properties for various applications.
Used in Agrochemical Industry:
Benzothiazole, 5,6-dimethoxy(9CI) is employed as an intermediate in the synthesis of agrochemicals, where its chemical structure plays a role in developing compounds for agricultural use, such as pesticides or herbicides.
Used in Antimicrobial and Antifungal Applications:
Due to its potential biological activities, Benzothiazole, 5,6-dimethoxy(9CI) is used as an antimicrobial and antifungal agent, serving in various applications where control of microbial growth is necessary, such as in medical, food preservation, or environmental sanitation contexts.

Upstream product

• 64-18-6 formic acid 
• 58249-73-3 bis-(4,5-dimethoxy-2-nitro-phenyl)-disulfane 
• 67-68-5 dimethyl sulfoxide 
• 6315-89-5 3,4-dimethoxyaniline 

Downstream Products

• 6294-52-6 SKA-17 

Relevant academic research and scientific papers

K2S as Sulfur Source and DMSO as Carbon Source for the Synthesis of 2-Unsubstituted Benzothiazoles

We describe a three-component reaction of o-iodoanilines with K2S and DMSO that provides 2-unsubstituted benzothiazoles in moderate to good isolated yields with good functional group tolerance. Electron-rich aromatic amines and o-phenylenediamines instead of o-iodoanilines provided 2-unsubstituted benzothiazoles and 2-unsubstituted benzimidazoles with and without K2S under similar conditions. Notably, DMSO plays three vital roles: carbon source, solvent, and oxidant.

Method for synthesizing benzothiazole compound by taking halogen-free aromatic amine as substrate

The invention discloses a method for synthesizing a benzothiazole compound by taking halogen-free aromatic amine as a substrate. The synthesis method comprises the following steps: adding an aromaticamine compound, potassium sulfide, dimethyl sulfoxide, an additive 1 and an additive 2 into a reaction tube, carrying out a stirring reaction at 120-150 DEG C, cooling to room temperature after the reaction is finished, and separating and purifying the product to obtain the benzothiazole compound. According to the reaction, an aromatic amine compound is used as a substrate, sulfuration as a sulfursource and dimethyl sulfoxide as a carbon source, the reaction conditions are relatively mild, and a metal catalyst is not needed. The invention develops the method for synthesizing the benzothiazolecompound, which is simple to operate and economical in atom.