5829-84-5Relevant academic research and scientific papers
Atom-transfer radical addition reactions catalyzed by RuCp* complexes: A mechanistic study
Fernandez-Zumel, Mariano A.,Thommes, Katrin,Kiefer, Gregor,Sienkiewicz, Andrzej,Pierzchala, Katarzyna,Severin, Kay
, p. 11601 - 11607 (2009)
Kinetic and spectroscopic analyses were performed to gain information about the mechanism of atomtransfer radical reactions catalyzed by the complexes [RuCl2Cp*(PPh3)] and [RuClCp*(PPh 3)2] (Cp* = pentamethylcyc
Olefin cyclopropanations via sequential atom transfer radical addition-dechlorination reactions
Thommes, Katrin,Severin, Kay
scheme or table, p. 188 - 190 (2011/07/07)
In organic synthesis, cyclopropanation reactions are often performed with Simmons-Smith-type reagents or by transition metal catalyzed reactions of olefins with diazo compounds. A novel method for the synthesis of substituted cyclopropanes is described that is based on a two-step reaction sequence. Olefins are reacted with 1,1'-dichlorides in a Ru-catalyzed atom transfer radical addition (ATRA) process and the resulting 1,3-dichlorides are directly converted into cyclopropanes by reductive coupling with magnesium. This one-pot procedure is applicable to a variety of substrates and can be performed in an inter- or intramolecular fashion. Schweizerische Chemische Gesellschaft.
