58306-67-5

Usage

Uses

Used in Medicinal Chemistry:
N-[2-amino-5-(phenylthio)phenyl]-2-methoxyacetamide is used as a potential pharmaceutical agent due to its distinctive molecular structure. Its amino and phenylthio groups may contribute to its interaction with biological targets, offering opportunities for the development of new drugs or therapeutic agents.
Used in Organic Synthesis:
As a building block in organic synthesis, N-[2-amino-5-(phenylthio)phenyl]-2-methoxyacetamide can be utilized to create a variety of complex organic compounds. Its functional groups provide versatility in chemical reactions, facilitating the synthesis of new molecules with potential applications in various industries.
Used in Research and Development:
In the field of scientific research, N-[2-amino-5-(phenylthio)phenyl]-2-methoxyacetamide serves as a subject for study, helping researchers to understand its properties, reactivity, and potential uses. This knowledge can be applied to innovate and develop new technologies and products in multiple sectors.

InChI:InChI=1/C15H16N2O2S/c1-19-10-15(18)17-14-9-12(7-8-13(14)16)20-11-5-3-2-4-6-11/h2-9H,10,16H2,1H3,(H,17,18)

Upstream product

• 108-90-7 chlorobenzene 
• 43156-47-4 2-nitro-5-phenylthioaniline 
• 108-86-1 bromobenzene 
• 63470-85-9 2-methoxy-N-(2-nitro-5-(phenylsulfanyl)phenyl)acetamide 

Downstream Products

• 58306-30-2 Febantel 
• 58306-33-5 C₂₁H₂₄N₄O₆S 
• 73851-07-7 C₂₀H₂₂N₄O₇S 

Relevant academic research and scientific papers

Preparation method of 2-amino-5-phenylthio-(2-methoxy)acetanilide

The invention belongs to the technical field of organic synthesis and particularly relates to a preparation method of 2-amino-5-phenylthio-(2-methoxy)acetanilide. According to the method, 2-nitro-5-(phenylthio)aniline is prepared from 2-nitro-5-mercaptoaniline and benzene halide and then subjected to a reaction with methyl methoxyacetate, 2-nitro-5-phenylthio-(2-methoxy)acetanilide is generated and subjected to catalytic hydrogenation reduction finally, and the target product is obtained. The preparation method has good reaction selectivity, and the obtained target product is high in purity and yield; use of high-toxicity materials is avoided, requirements for equipment and operation conditions are reduced, and safety and stability of the preparation method are improved; doses of the reaction materials are optimized, and excess benzene halide and methyl methoxyacetate can be recycled after being recovered simply; little solid waste is produced, waste treatment cost is reduced greatly,and the requirement for environmental protection is met.

Febantel, a new broad-spectrum anthelminthic

N {2 [2,3 Bis (methoxycarbonyl) guanidino] 5 (phenylthio) phenyl } 2 methoxyacetamide (febantel, Rintal) is a new compound which is highly active against various species of nematodes and cestodes in mice, rats, dogs, sheep and cattle. In sheep and cattle a single oral dose of 5 mg/kg resulted in an almost complete elimination of larval and adult intestinal nematodes as well as Dictyocaulus. The compound was well tolerated by all animals tested.

Substituted phenylisothioureas and processes for their preparation and use

N-[2-(Substituted amido)phenyl]-N'-carbonyl-S-substituted isothioureas bearing an optionally substituted phenoxy, phenylthio, phenylsulfinyl or phenylsulfonyl group in the 4- or 5-position of the 2-(substituted amido)-phenyl group are anthelmintic agents. The compounds, of which N-(2-acetamido-4-phenoxyphenyl)-N'-carbomethoxy-S-methylthiourea is a typical example, are prepared through the reaction of S-substituted N-(mercaptohalomethylene)carbamic acid ester and an apropriately substituted 2-aminoanilide, or through alkylation of the corresponding S-unsubstituted thiourea.