58316-11-3

Basic information

• Product Name: (2E)-3-(Dimethylamino)-1-(3-methoxyphenyl)-prop-2-en-1-one
• Synonyms: (2E)-3-(Dimethylamino)-1-(3-methoxyphenyl)-prop-2-en-1-one
• CAS NO: 58316-11-3
• Molecular Formula: C₁₂H₁₅NO₂
• Molecular Weight: 205.253
• Mol File: 58316-11-3.mol
• Article Data: 29

Chemical Properties

• Boiling Point: 186 °C(Press: 0.08 Torr)
• Appearance: /
• Density: 1.050±0.06 g/cm3(Predicted)
• PKA: 5.14±0.70(Predicted)
• CAS DataBase Reference: (2E)-3-(Dimethylamino)-1-(3-methoxyphenyl)-prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-3-(Dimethylamino)-1-(3-methoxyphenyl)-prop-2-en-1-one(58316-11-3)
• EPA Substance Registry System: (2E)-3-(Dimethylamino)-1-(3-methoxyphenyl)-prop-2-en-1-one(58316-11-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 58316-11-3(Hazardous Substances Data)

Usage

Uses

(2E)-3-(Dimethylamino)-1-(3-methoxyphenyl)prop-2-en-1-one

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 586-37-8 1-(3-Methoxyphenyl)ethanone 
• 506-59-2 N,N-dimethylammonium chloride 
• 109-94-4 formic acid ethyl ester 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 51594-60-6 1-(3-methoxyphenyl)prop-2-en-1-one 

Downstream Products

• 1203608-47-2 1-phenyl-5-(3-methoxyphenyl)pyrazole 
• 1203608-55-2 1-(2-bromophenyl)-5-(3-methoxyphenyl)pyrazole 
• 1477476-17-7 2-(6,6-dimethyl-5-oxo-5,6,7,8-tetrahydroquinolin-2-yl)-4-methoxylphenyl acetate 
• 1477476-03-1 4-methoxy-2-(5-oxo-5,6,7,8-tetrahydroquinolin-2-yl)phenyl acetate 
• 1477476-10-0 2-(7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinolin-2-yl)-4-methoxyphenyl acetate 
• 951907-73-6 6-(3-methoxy-phenyl)-1H-pyrazolo[3,4-b]pyridin-3-ylamine 
• 946601-96-3 2-chloro-6-(3-methoxy-phenyl)-nicotinonitrile 
• 142499-40-9 6-(3-methoxy-phenyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile 
• 52102-78-0 1-Chlor-2-(3-methoxybenzoyl)-3-carbethoxypropen 
• 112778-82-2 4-(3-methoxyphenyl)benzo[4,5]imidazo[1,2-a]pyrimidine 

Relevant articles and documents

DDQ-mediated oxidative coupling reaction of N,N-dimethyl enaminones with cycloheptatriene

An efficient 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ)-mediated oxidative coupling reaction of N,N-dimethyl enaminones with cycloheptatriene is developed. It provides a variety of α-alkenylated 1,3-dicarbonyl compounds in moderate to good yields under mild conditions.

Harnessing Stereospecific Z-Enamides through Silver-Free Cp?Rh(III) Catalysis by Using Isoxazoles as Masked Electrophiles

The stereospecific synthesis of Z-enamides is described in this paper. For the first time, isoxazoles have been employed as electrophiles in C-H functionalization to afford thermodynamically less stable Z-enamides utilizing salicylaldehydes in an atom- and step-economic fashion. The stereochemistry of enamides might originate from the relative disposition of atoms present in isoxazole and the intramolecular hydrogen bonding. The reaction showed excellent scope as several structurally and electronically diverse salicylaldehydes and isoxazoles reacted efficiently.

Rh(III)-Catalyzed Enaminone-Directed C-H Coupling with α-Diazo-α-phosphonoacetate for Reactivity Discovery: Fluoride-Mediated Dephosphonation for C-C Coupling Reactions

Rh(III)-catalyzed enaminone-directed C-H coupling with α-diazo-α-phosphonoacetate has been used for the identification of fluoride-mediated dephosphonation C-C coupling reactivity for the synthesis of 4-hydroxy-1-naphthoates. Intermolecular C-C coupling of α-phosphonoacetate and benzaldehyde for (E)-selective α,β-unsaturated ester synthesis has also been achieved.