58379-85-4 Usage
Uses
Used in Organic Chemistry:
1-Allyl-1-Tosylmethyl Isocyanide is used as a building block for the synthesis of more complex organic structures due to its unique isocyanide group and sulfonyl functionality. This allows for the creation of a wide range of compounds with various applications in different industries.
Used in Pharmaceutical Industry:
1-Allyl-1-Tosylmethyl Isocyanide is used as a key intermediate in the synthesis of pharmaceutical compounds. Its specific structural features enable the development of new drugs with potential therapeutic applications, such as in the treatment of various diseases and medical conditions.
Used in Material Science:
1-Allyl-1-Tosylmethyl Isocyanide is used as a precursor in the development of new materials with unique properties. Its incorporation into the synthesis process can lead to the creation of advanced materials with improved performance characteristics, such as enhanced stability, reactivity, or selectivity.
Used in Research and Development:
1-Allyl-1-Tosylmethyl Isocyanide is used as a research tool in academic and industrial laboratories. Its unique structure and reactivity make it an interesting subject for studying various chemical reactions and processes, which can contribute to the advancement of scientific knowledge and the development of new technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 58379-85-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,3,7 and 9 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 58379-85:
(7*5)+(6*8)+(5*3)+(4*7)+(3*9)+(2*8)+(1*5)=174
174 % 10 = 4
So 58379-85-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H13NO2S/c1-4-5-12(13-3)16(14,15)11-8-6-10(2)7-9-11/h4,6-9,12H,1,5H2,2H3
58379-85-4Relevant academic research and scientific papers
One-pot Van Leusen synthesis of 4,5-disubstituted oxazoles in ionic liquids
Wu, Bo,Wen, Jun,Zhang, Ji,Li, Jing,Xiang, Yong-Zhe,Yu, Xiao-Qi
experimental part, p. 500 - 504 (2009/08/07)
An efficient and mild protocol for the preparation of 4,5-disubstituted oxazoles through an improved one-pot van Leusen oxazole synthesis in ionic liquids is described. The oxazole products were prepared from tosylmethyl isocyanide (TosMIC), aliphatic hal
Synthesis and structure-activity relationship of a new series of COX-2 selective inhibitors: 1,5-Diarylimidazoles
Almansa, Carmen,Alfón, José,De Arriba, Alberto F.,Cavalcanti, Fernando L.,Escamilla, Ignasi,Gómez, Luis A.,Miralles, Agustí,Soliva, Robert,Bartrolí, Javier,Carceller, Elena,Merlos, Manuel,García-Rafanell, Julián
, p. 3463 - 3475 (2007/10/03)
The synthesis and the pharmacological activity of a series of 1,5-diarylimidazoles developed as potent and selective cyclooxygenase-2 (COX-2) inhibitors are described. The new compounds were evaluated both in vitro (COX-1 and COX-2 inhibition in human whole blood) and in vivo (carrageenan-induced paw edema, air-pouch, and hyperalgesia tests). Modification of all the positions of two regioisomeric imidazole cores led to the identification of 4-[4-chloro-5-(3-fluoro4-methoxyphenyl)imidazol-1-yl]benzenesulfonamide (UR-8880, 51f) as the best candidate, which is now undergoing Phase I clinical trials.
