583883-36-7

Basic information

• Product Name: C₂₄H₂₄Cl₂FN₃O₄
• CAS NO: 583883-36-7
• Molecular Weight: 508.377
• Mol File: 583883-36-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₄Cl₂FN₃O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₄Cl₂FN₃O₄(583883-36-7)
• EPA Substance Registry System: C₂₄H₂₄Cl₂FN₃O₄(583883-36-7)

Safety Data

• Hazardous Substances Data: 583883-36-7(Hazardous Substances Data)

Upstream product

• 500859-56-3 (2R)-1-amino-3-[4-(3,4-dichlorophenoxy)piperidin-1-yl]propan-2-ol 
• 583880-88-0 6-fluoro-1-oxo-1,2-dihydroisoquinoline-4-carboxylic acid 
• 583880-92-6 methyl 6-fluoro-1-oxo-2H-isoquinoline-4-carboxylate 
• 583880-91-5 C₁₁H₇FO₄ 
• 500779-09-9 2-(carboxymethyl)-4-fluorobenzoic acid 

Relevant articles and documents

Discovery and evolution of phenoxypiperidine hydroxyamide dual CCR3/H 1 antagonists. Part II: Optimising in vivo clearance

The second part of this communication focuses on the resolution of issues surrounding the series of hydroxyamide phenoxypiperidine CCR3/H1 dual antagonists described in Part I. This involved further structural exploration directed at reducing m