583960-72-9

Basic information

• Product Name: Cyclopentanone, 3-(3-chlorophenyl)-, (3R)-
• CAS NO: 583960-72-9
• Molecular Formula: C11H11ClO
• Molecular Weight: 194.661
• Mol File: 583960-72-9.mol

Chemical Properties

• CAS DataBase Reference: Cyclopentanone, 3-(3-chlorophenyl)-, (3R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanone, 3-(3-chlorophenyl)-, (3R)-(583960-72-9)
• EPA Substance Registry System: Cyclopentanone, 3-(3-chlorophenyl)-, (3R)-(583960-72-9)

Safety Data

• Hazardous Substances Data: 583960-72-9(Hazardous Substances Data)

Upstream product

• 930-30-3 cyclopent-2-enone 
• 5720-07-0 4-methoxyphenylboronic acid 
• 63503-60-6 3-chlorophenylboronic acid 

Relevant articles and documents

Room-temperature rhodium-catalyzed asymmetric 1,4-addition of potassium trifluoro(organo)borates

For the first time the room-temperature rhodium-catalyzed asymmetric 1,4-addition of potassium aryltrifluoroborates to αβ-unsaturated substrates is described. Thanks to the use of a chiral diene as ligand for rhodium and triethylamine as base, to facilita

Chiral bis-phosphoramidites based on linked-BINOL for rhodium-catalyzed 1,4-addition of arylboronic acids to α,β-unsaturated carbonyl compounds

Cationic rhodium(I) complex prepared from Shibasaki's linked-BINOL and [Rh(nbd)2]BF4 catalyzed asymmetric 1,4-addition of arylboronic acids to enones at room temperature with high enantioselectivities up to 99.8%ee. Copyright

Chiral [2.2.2] dienes as ligands for Rh(I) in conjugate additions of boronic acids to a wide range of acceptors

We document a series of investigations that led to new substituted [2.2.2]-diene ligands which display high selectivity in Rh(I)-catalyzed conjugate addition reactions to substrates not previously examined with diene ligands. Moreover, we disclose an unexpected, interesting effect that results from the introduction of a third C=C onto the ligand scaffold (cf. 1).

Rhodium-catalyzed 1,4-addition of arylboronic acids to α,β-unsaturated carbonyl compounds: Large accelerating effects of bases and ligands

The effects of ligands and bases in the rhodium(I)-catalyzed 1,4-addition of arylboronic acids to α,β-unsaturated carbonyl compounds were reinvestigated to carry out the reaction under mild conditions. Rhodium(I) complexes possessing a 1,5-cyclooctadiene (cod) and a hydroxo ligand such as [RhOH(cod)]2 exhibited excellent catalyst activities compared to those of the corresponding rhodium-acac or -chloro complexes and their phosphine derivatives. The reaction was further accelerated in the presence of KOH, thus allowing the 1,4-addition even at 0 °C. A cationic rhodium-(I)-(R)-binap complex, [Rh(R-binap)(nbd)]BF4, catalyzed the reaction at 25-50 °C in the presence of Et3N with high enantioselectivities of up to 99% ee for α,β-unsaturated ketones, 92% for aldehydes, 94% for esters, and 92% for amides.