584-82-7

Basic information

• Product Name: 2-ALLYL-4-METHOXYPHENOL
• Synonyms: 2-(2-Propenyl)-4-methoxyphenol;4-Methoxy-2-allylphenol;Nsc404069;Phenol, 2-allyl-4-methoxy-;Phenol, 4-methoxy-2-(2-propenyl)-;Wln: 1U2R bq eo1;4-methoxy-2-(prop-2-en-1-yl)phenol
• CAS NO: 584-82-7
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.2
• Mol File: 584-82-7.mol
• Article Data: 53

Chemical Properties

• Boiling Point: 274.8°C at 760 mmHg
• Flash Point: 133.2°C
• Appearance: /
• Density: 1.05g/cm³
• Vapor Pressure: 0.00315mmHg at 25°C
• Refractive Index: 1.535
• PKA: 10.78±0.18(Predicted)
• CAS DataBase Reference: 2-ALLYL-4-METHOXYPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ALLYL-4-METHOXYPHENOL(584-82-7)
• EPA Substance Registry System: 2-ALLYL-4-METHOXYPHENOL(584-82-7)

Safety Data

• Hazardous Substances Data: 584-82-7(Hazardous Substances Data)

Usage

Chemical compound

2-ALLYL-4-METHOXYPHENOL

Physical appearance

Pale yellow, oily liquid

Aroma

Pleasant, spicy

Found in

Essential oils such as clove oil, nutmeg, and cinnamon

Applications

Flavoring agent in food and beverages
Fragrance in perfumes and cosmetics
Topical analgesic and antiseptic in medicine

Properties

Antioxidant
Anti-inflammatory
Antimicrobial

Use in

Pharmaceuticals
Personal care products

Other uses

Synthesis of other chemicals
Fumigant to control pests in agriculture

Caution

Can cause skin and respiratory irritations in high concentrations

InChI:InChI=1/C10H12O2/c1-3-4-8-7-9(12-2)5-6-10(8)11/h3,5-7,11H,1,4H2,2H3

Upstream product

• 101-84-8 diphenylether 
• 13391-35-0 allyl (4-methoxyphenyl) ether 
• 111-90-0 ethoxyethoxyethanol 
• 150-76-5 4-methoxy-phenol 
• 123-31-9 hydroquinone 
• 1746-13-0 allyl phenyl ether 
• 106-95-6 allyl bromide 
• 37592-19-1 3-allyloxyanisole 
• 959697-71-3 2-allyl-4-methoxy-1-prop-2-ynyloxy-benzene 
• 4873-09-0 allyl tosylate 
• 121-69-7 N,N-dimethyl-aniline 

Downstream Products

• 17398-03-7 4-methoxy-2-(1-propenyl)phenol 
• 100117-70-2 2-allyl-4-methoxyphenyl acetate 
• 19754-22-4 2-allyl-1,4-dimethoxybenzene 
• 272125-04-9 4-methoxy-2-(4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluoro-2-iodo-nonyl)-phenol 
• 1219499-12-3 2-allyl-1-(3-methyl-butoxy)-4-methoxybenzene 
• 100256-37-9 2-allyl-1-ethoxy-4-methoxybenzene 
• 1219499-05-4 2-allyl-4-methoxy-1-propoxybenzene 
• 205433-77-8 2-allyl-1-allyloxy-4-methoxy-benzene 
• 1219499-08-7 2-allyl-1-butoxy-4-methoxybenzene 
• 1558056-38-4 2-allyl-4-methoxyphenyl ethyl allylphosphonate 
• 1558056-48-6 2-allyl-4-methoxyphenyl ethyl vinylphosphonate 
• 67903-03-1 2,6-di(3-methyl-2-butenyl)benzene-1,4-diol 
• 107390-44-3 3-[4-acetoxy-3,5-bis(3-methyl-2-butenyl)phenyl]-(2E)-propenoic acid methyl ester 
• 72944-19-5 artepillin C 

Relevant articles and documents

Allylphenols as a new class of human 15-lipoxygenase-1 inhibitors

In this study, a series of mono- and diallylphenol derivative were designed, synthesized, and evaluated as potential human 15-lipoxygenase-1 (15-hLOX-1) inhibitors. Radical scavenging potency of the synthetic allylphenol derivatives was assessed and the results were in accordance with lipoxygenase (LOX) inhibition potency. It was found that the electronic natures of allyl moiety and para substituents play the main role in radical scavenging activity and subsequently LOX inhibition potency of the synthetic inhibitors. Among the synthetic compounds, 2,6-diallyl-4-(hexyloxy)phenol (42) and 2,6-diallyl-4-aminophenol (47) showed the best results for LOX inhibition (IC50 = 0.88 and 0.80 μM, respectively).

TRICYCLIC FURAN-SUBSTITUTED PIPERIDINEDIONE COMPOUND

Disclosed are a series of tricyclic furan-substituted piperidinedione compounds and an application thereof in preparing a drug for treating a disease related to CRBN protein. In particular, disclosed is a derivative compound represented by formula (I) or a pharmaceutically acceptable salt thereof.

Investigating the microwave-accelerated Claisen rearrangement of allyl aryl ethers: Scope of the catalysts, solvents, temperatures, and substrates

The microwave-accelerated Claisen rearrangement of allyl aryl ethers was investigated, in order to gain insight into the scope of the catalysts, solvents, temperatures, and substrates. Among the catalysts examined, phosphomolybdic acid (PMA) was found to greatly accelerate the reaction in NMP, at temperatures ranging from 220 to 300 °C. This method was found to be useful for preparing several intermediates previously reported in the literature using precious metal catalysts such as Au(I), Ag(I), and Pt(II). Additionally, substrates bearing bromo and nitro groups on the aryl portion required careful tailoring of the reaction conditions to avoid complex product profiles.