58462-31-0Relevant academic research and scientific papers
RNAs Containing Carbocyclic Ribonucleotides
Akabane-Nakata, Masaaki,Chickering, Tyler,Egli, Martin,Harp, Joel M.,Manoharan, Muthiah,Matsuda, Shigeo,Schlegel, Mark K.
supporting information, (2022/01/12)
Toward the goal of evaluation of carbocyclic ribonucleoside-containing oligonucleotide therapeutics, we developed convenient, scalable syntheses of all four carbocyclic ribonucleotide phosphoramidites and the uridine solid-support building block. Crystall
Biocatalytical Transformations- VI. The 4-Acetamido-cyclopent-2-ene Carboxylate Route Revisited: Synthesis of (+)- and (-)-Aristeromycin
Csuk, Rene,Doerr, Petra
, p. 5789 - 5798 (2007/10/02)
Enantiomerically pure (+)-as well as (-)-aristeromycin can be synthesized starting from (+)- or (-)-butyl (or hexyl) 4-acetamido-cyclopent-2-ene carboxylate; these carboxylates are easily obtained from their corresponding racemates by hydrolysis with the lipase from Candida rugosa.
