58464-06-5

Upstream product

• 7228-47-9 2-(2-naphthyl)ethanol 
• 2524-64-3 chlorophosphoric acid diphenyl ester 
• 546-68-9 titanium(IV)isopropoxide 

Downstream Products

• 7228-47-9 2-(2-naphthyl)ethanol 
• 827-54-3 2-naphthylethylene 
• 23189-64-2 1,2,4-Trimethyl-phenanthren 
• 1433777-47-9 (R)-1-(4-methoxyphenyl)-4-(naphthalen-2-yl)pentan-3-one 
• 93-08-3 methyl 2-naphthyl ketone 
• 1424035-17-5 (S)-2-(1-(4-methoxyphenyl)ethyl)naphthalene 
• 1442898-25-0 (R)-2-(1-(4-methoxyphenyl)ethyl)naphthalene 
• 1416981-95-7 (S)-methyl 4-(1-(naphthalen-2-yl)ethyl)benzoate 

Relevant academic research and scientific papers

An improved method for Lewis acid catalyzed phosphoryl transfer with Ti(t-BuO)4

Several inorganic esters have been evaluated as phosphoryl transfer catalysts. Of these, Ti(t-BuO)4 was found to be the most effective catalyst giving excellent yields of the desired phosphate esters. The loading of the catalyst could be reduced to a little as 5 mol % for a majority of substrates with no loss in the yield of product. This methodology is significantly more versatile than using TiCl4 and is suitable for the phosphorylation of more complex carbohydrates and molecules of biological interest.

A simple and effective method for phosphoryl transfer using TiCl4 catalysis

(graph presented) A number of Lewis acids have been evaluated as catalysts for the phosphoryl transfer, the most efficient being TiCl4. Application of this methodology to the phosphorylation of a number of representative target alcohols is presented.