5848-20-4Relevant academic research and scientific papers
Biosynthesis of [14C]-11-De-O-Methyltomaymycin, a Precursor of Radiolabelled Antibody Drug Conjugates
Aubert, Catherine,Lavisse, Mélanie,Roy, Sebastien
, p. 2424 - 2429 (2021/06/09)
Antibody drug conjugates (ADCs) are one of the most promising technologies to treat cancer as they combine the specificity of an antibody with the high potency of a cytotoxic molecule such as tomaymycin derivatives, which are DNA-interactive antitumor ant
Fast and efficient synthesis of 14C labelled benzonitriles and their corresponding acids
Schou, Soren Christian
experimental part, p. 173 - 176 (2010/07/02)
14C-Anthranilic acid has been prepared in a fast and efficient way in a two-step reaction in 82% overall radiochemical yield. Thus, 2-iodoaniline was transformed into 2-amino-[7-14C]-benzonitrile using a palladium catalyzed cyanation
Synthesis of a series of carbon-14 labelled 4-aminoquinazolines and quinazolin-4 (3H)-ones
Saemian, Nader,Arjomandi, Omid Khalili,Shirvani, Gholamhossein
experimental part, p. 453 - 456 (2010/07/08)
4-Aminoquinazolines and quinazolin-4 (3H)-ones, both labelled with carbon-14 in the 4-position, were prepared from 2-aminobenzonitrile-[cyano- 14C] and 2-aminobenzoic acid-[carboxy -14C] or 2-amino- benzamide-[carboxy -14C
