DL-erythro-Methyl-3-(3-methyl-4,5-diphenyl-pentan-3,4-diol-2,5-dion)-cyclophosphat, also known as Troger's base, is a complex organic compound with the molecular formula C19H21O5P. It is a key intermediate in the synthesis of various phosphorus-containing compounds, particularly in the production of cyclophosphamide, a widely used alkylating agent in cancer chemotherapy. Troger's base is synthesized through a series of chemical reactions involving the condensation of formaldehyde, acetone, and phosphorus trichloride, followed by hydrolysis and methylation. Its structure features a cyclophosphamide core with a methyl group attached to the phosphorus atom, and a 3-methyl-4,5-diphenyl-pentan-3,4-diol-2,5-dione moiety. Due to its importance in pharmaceutical chemistry, Troger's base has been extensively studied for its chemical properties, reactivity, and potential applications in drug development.
5848-81-7
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Basic information
- Product Name: DL-erythro-Methyl-3-(3-methyl-4.5-diphenyl-pentan-3.4-diol-2.5-dion)-cyclophosphat
- Synonyms:
- CAS NO:5848-81-7
- Molecular Formula:
- Molecular Weight: 374.33
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: DL-erythro-Methyl-3-(3-methyl-4.5-diphenyl-pentan-3.4-diol-2.5-dion)-cyclophosphat(CAS DataBase Reference)
- NIST Chemistry Reference: DL-erythro-Methyl-3-(3-methyl-4.5-diphenyl-pentan-3.4-diol-2.5-dion)-cyclophosphat(5848-81-7)
- EPA Substance Registry System: DL-erythro-Methyl-3-(3-methyl-4.5-diphenyl-pentan-3.4-diol-2.5-dion)-cyclophosphat(5848-81-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 5848-81-7(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 5848-81-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,8,4 and 8 respectively; the second part has 2 digits, 8 and 1 respectively.Calculate Digit Verification of CAS Registry Number 5848-81:
(6*5)+(5*8)+(4*4)+(3*8)+(2*8)+(1*1)=127
127 % 10 = 7
So 5848-81-7 is a valid CAS Registry Number.
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DL-erythro-Methyl-3-(3-methyl-4.5-diphenyl-pentan-3.4-diol-2.5-dion)-cyclophosphat
