58491-51-3Relevant academic research and scientific papers
Preparation and application of 2-(4-substituted phenyl)-3-formamide benzofuranene cyanide compound
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, (2019/04/17)
The invention provides a preparation and application of a 2-(4-substituted phenyl)-3-formamide benzofuranene cyanide compound. The benzofuranene cyanide compound shown in formula I has a structure shown in the following formula I, wherein the definition o
Synthesis, biological evaluation and molecular docking analysis of 2-phenyl-benzofuran-3-carboxamide derivatives as potential inhibitors of Staphylococcus aureus Sortase A
He, Wan,Zhang, Yong,Bao, Jian,Deng, Xinxian,Batara, Jennifer,Casey, Shawn,Guo, Qiuyuan,Jiang, Faqin,Fu, Lei
, p. 1341 - 1351 (2017/02/18)
In Gram-positive bacteria, Sortase A (Srt A) is a critical cysteine transpeptidase that is responsible for recognizing and assembling surface virulence proteins through the recognition of a LPXTG (leucine, proline, X, threonine, and glycine, where X is an
Benzofuran compound, preparation method and applications thereof
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, (2016/10/08)
The present invention provides a benzofuran compound, a preparation method and applications thereof, wherein the structure is represented by a general formula (I-1) or (I-2), R1, R3 and R4 are any one selected from hydrogen, C1-C5 straight or branched cha
Benzofuran compounds intermediates, and preparation method and application thereof
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, (2016/12/01)
The invention provides a kind of benzofuran compounds intermediates, and a preparation method and application thereof, and the structure of the intermediates is shown as a general formula (I) in the specification. In the general formula (I), R1 and R3 are
A novel efficient protocol for preparation of 3-formyl-2-arylbenzo[b]furan derivatives
Liao, Benren,Ruan, Libo,Shi, Min,Li, Nian,Chang, Liang,Liu, Leping,Yang, Fan,Tang, Jie
, p. 3274 - 3277 (2014/06/09)
An efficient method for preparation of 3-formyl-2-arylbenzo[b]furan derivatives 4 from 3-chloro-2-(2-methoxyaryl)-1-arylprop-2-en-1-one 2 was developed, and the desired product was obtained in good to excellent yields. By converting 2-(2-methoxyphenyl)-3-oxo-3-phenylpropanal 1 to 2, the regioselectivity problem occurring in the reaction when using 1 as the starting material was successfully avoided. Furthermore, a one-pot procedure for the successive demethylation, cyclization, and hydrolysis was evolved, although the intermediate 3-(dibromomethyl)-2-phenylbenzo[b]furan 3a could be isolated. A plausible mechanism was proposed based on some in situ investigations.
