58501-82-9Relevant academic research and scientific papers
Synthesis and antiviral activity of novel spirocyclic nucleosides
Cobb, Alexander J. A.,Dell'Isola, Antonio,Abdulsattar, Ban O.,McLachlan, Matthew M. W.,Neuman, Benjamin W.,Müller, Christin,Shankland, Kenneth,Al-Mulla, Hawaa M. N.,Binks, Alexander W. D.,Elvidge, Warren
, p. 18363 - 18380 (2018/11/23)
The synthesis of a number of spirocyclic ribonucleosides containing either a triazolic or azetidinic system is described, along with two analogous phosphonate derivatives of the former. These systems were constructed from the same β-d-psicofuranose starti
Synthesis and antiviral properties of spirocyclic [1,2,3]-Triazolooxazine nucleosides
Dell'Isola, Antonio,McLachlan, Matthew M. W.,Neuman, Benjamin W.,Al-Mullah, Hawaa M. N.,Binks, Alexander W. D.,Elvidge, Warren,Shankland, Kenneth,Cobb, Alexander J. A.
, p. 11685 - 11689 (2014/10/15)
An efficient synthesis of spirocyclic triazolooxazine nucleosides is described. This was achieved by the conversion of β-D-psicofuranose to the corresponding azido-derivative, followed by alkylation of the primary alcohol with a range of propargyl bromide
