5854-73-9Relevant academic research and scientific papers
INHIBITORS OF PRENYL-PROTEIN TRANSFERASE
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Page column 41, (2010/01/21)
The present invention comprises piperazine/piperazinone-containing compounds having multicyclic ring system substituents on one of the piperazine/piperazinone nitrogens, which inhibit prenyl-protein transferases, including farnesyl-protein transferase and geranylgeranyl-protein transferase type I. Such therapeutic compounds are useful in the treatment of cancer
