58544-90-4

Basic information

• Product Name: 2-(3,4-dimethoxyphenyl)-3-hydroxy-7-methoxy-4H-chromen-4-one
• Synonyms: 4H-1-benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3-hydroxy-7-methoxy-
• CAS NO: 58544-90-4
• Molecular Formula: C₁₈H₁₆O₆
• Molecular Weight: 328.316
• Mol File: 58544-90-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 500.3°C at 760 mmHg
• Flash Point: 182.2°C
• Density: 1.333g/cm³
• Vapor Pressure: 7.9E-11mmHg at 25°C
• Refractive Index: 1.613
• CAS DataBase Reference: 2-(3,4-dimethoxyphenyl)-3-hydroxy-7-methoxy-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-dimethoxyphenyl)-3-hydroxy-7-methoxy-4H-chromen-4-one(58544-90-4)
• EPA Substance Registry System: 2-(3,4-dimethoxyphenyl)-3-hydroxy-7-methoxy-4H-chromen-4-one(58544-90-4)

Safety Data

• Hazardous Substances Data: 58544-90-4(Hazardous Substances Data)

Usage

General Description

The chemical "2-(3,4-dimethoxyphenyl)-3-hydroxy-7-methoxy-4H-chromen-4-one" is a compound belonging to the family of flavonoids, which are known for their antioxidant and anti-inflammatory properties. This particular compound contains a chromen-4-one backbone with a 2-(3,4-dimethoxyphenyl) group attached to it, as well as hydroxy and methoxy substituents at specific positions. It has potential pharmacological applications due to its reported antioxidant, anti-cancer, and anti-inflammatory properties. Additionally, it may have potential as a natural source for drug development due to its diverse biological activities. These properties make this compound an important subject for further research in the field of medicinal chemistry and drug discovery.

Upstream product

• 57601-14-6 2'-hydroxy-3,4,4'-trimethoxychalcone 
• 10493-06-8 3-(3,4-dimethoxyphenyl)-1-(2-hydroxy-4-methoxyphenyl)-2-propen-1-one 
• 552-41-0 1-(2-hydroxy-4-methoxyphenyl)ethanone 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Downstream Products

• 528-48-3 3,7,3',4'-tetrahydroxyflavone 
• 17093-86-6 3,3',4',7-tetra-O-methylfisetin 

Relevant articles and documents

Structure-activity relationship and pharmacokinetic studies of 3-O-substitutedflavonols as anti-prostate cancer agents

Thirty-eight 3-O-substituted-3′,4′-dimethoxyflavonols and twenty-five 3-O-substituted-3′,4′,7-trimethoxyflavonols have been synthesized for systematic investigation on the structure-activity relationships of 3-O-substituted-3′,4′-dimethoxyflavonols in thr

Inhibition of prostaglandin E2 production by synthetic minor prenylated chalcones and flavonoids: Synthesis, biological activity, crystal structure, and in silico evaluation

The discovery of potent inhibitors of prostaglandin E2 (PGE 2) synthesis in recent years has been proven to be an important game changer in pharmaceutical industry. It is known that excessive production of PGE2 triggers a

Isolation and synthesis of flavonols and comparison of their antioxidant activity

Phytochemical investigation of the leaves of Astragalus beckari yielded four flavonol aglycones, namely kaempferol, quercetin, 5-deoxy kaempferol and fisitin. These isolated compounds were then synthesised in the laboratory using the Algar-Flyn-Oyamad reaction. Antioxidant activity of both the isolated and synthesised flavonoids was compared using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay method. The isolated flavonoids were found to be more active.