58545-34-9

Usage

Structure

A brominated derivative of resorcinol

Pharmaceuticals

Used in the pharmaceutical industry

Cosmetics

Commonly used in cosmetics

Organic synthesis

Potential uses in organic synthesis

Medicinal chemistry

Potential uses in medicinal chemistry due to unique structure and properties

Antibacterial

Exhibits antibacterial properties

Antifungal

Exhibits antifungal properties

Biologically active molecules

Used in the synthesis of biologically active molecules

Starting material

Can be a starting material for the preparation of various pharmaceuticals and agrochemicals

Upstream product

• 58545-33-8 1-(3,5-dimethoxyphenyl)-5-phenoxypentane 
• 886-52-2 5-(5'-bromopentyl)-1,3-dimethoxybenzene 
• 58545-32-7 1-(3,5-dimethoxyphenyl)-5-phenoxy-1-pentene 
• 197178-54-4 5-(3,5-dimethoxyphenyl)pentanoic acid ethyl ester 
• 836-27-1 1,3-dimethoxy-5-(5-hydroxypentyl)benzene 
• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 870789-90-5 1-(3,5-dimethoxyphenyl)-5-phenoxypentan-1-ol 

Downstream Products

• 1972-08-3 dronabinol 

Relevant academic research and scientific papers

Δ9-tetrahydrocannabinol immunochemical studies: Haptens, monoclonal antibodies, and a convenient synthesis of radiolabeled Δ9-tetrahydrocannabinol

Immunopharmacotherapy as an approach to combat drugs of abuse has become an active area of investigation. Marijuana is the most commonly used illicit drug in the U.S. The main active chemical in marijuana is Δ9- tetrahydrocannabinol (Δ9-THC); hence, monoclonal antibodies with high affinity and specificity for Δ9-tetrahydrocannabinol could be valuable immunopharmacotherapeutic intervention and diagnostic tools. We have synthesized immunoconjugates that induce an effective immune response to Δ9-THC and describe a convenient synthesis of radiolabeled Δ9-THC. We demonstrate the value and use of this probe to select anti-Δ9-THC antibodies that bind Δ9-THC with good affinity. The synthetic route to radiolabeled Δ9-THC has enabled the correct assessment of the affinity of these antibodies to their ligand and may facilitate future binding studies between Δ9- THC and its analogues and the cannabinoid receptors.