58556-75-5Relevant articles and documents
Enantioselective α-Benzylation of Acyclic Esters Using π-Extended Electrophiles
Schwarz, Kevin J.,Yang, Chao,Fyfe, James W. B.,Snaddon, Thomas N.
supporting information, p. 12102 - 12105 (2018/09/11)
The first asymmetric cooperative Lewis base/palladium catalyzed benzylic alkylation of acyclic esters is reported. This reaction proceeds via stereodefined C1-ammonium enolate nucleophiles. Critical to its success was the identification of benzylic phosphate electrophiles, which were uniquely reactive. Alkylated products were obtained with very high levels of enantioselectivity, and this method has been applied toward the synthesis of the thrombin inhibitor DX-9065a.
The effect of substituents on the syn-anti conformer ratio in naphthyl-based imidazolinium salts and their corresponding N-heterocyclic carbenes
Gatti, Michele,Wu, Linglin,Drinkel, Emma,Gaggia, Fiona,Blumentritt, Sascha,Linden, Anthony,Dorta, Reto
experimental part, p. 176 - 198 (2011/06/18)
Eight new N-heterocyclic carbenes (NHCs) featuring substituted naphthyl side chains were synthesized. These molecules are present in solution as a stable mixture of anti and syn conformers. Through careful tuning of the substituents on position 2 and 2,7
Synthesis of a Helical Ferrocene
Katz, Thomas J.,Pesti, Jaan
, p. 346 - 347 (2007/10/02)
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